膳食纤维、肠道微生物与动物健康关系的研究进展OA
Research Progress on Relationships between Dietary Fiber,Gut Microbiota and Animal Health
肠道微生物在动物消化吸收、免疫调控及代谢稳态中发挥关键作用,与宿主形成深度共生关系,其代谢产物可影响远端器官功能.膳食纤维作为不能被宿主消化酶降解但可被肠道微生物利用的复合碳水化合物,其生物学功能依赖于与肠道微生物的互作.膳食纤维经肠道微生物发酵产生的短链脂肪酸等代谢产物,通过调控肠上皮屏障功能、免疫反应及代谢通路,影响宿主的肠道健康、机体代谢、繁殖发育及衰老过程;同时,动物宿主的消化能力与免疫状态也影响膳食纤维的利用效率及肠道微生物结构.动态共生网络的失衡,如膳食纤维不足或肠道菌群失调,可导致动物宿主代谢紊乱、炎症反应及多种疾病的发生.本文系统阐述了膳食纤维、肠道微生物与动物宿主之间通过"底物供给-代谢调控-环境适应"机制形成的动态共生网络,并深入解析膳食纤维-肠道微生物-动物宿主三者间的复杂互作路径,旨在为动物营养调控与肠道健康管理提供理论依据.
Gut microbiota plays a crucial role in animal digestion and absorption,immune regulation,and met-abolic homeostasis,forming a deep symbiotic relationship with the host.Their metabolic products can affect the function of distant organs.Dietary fiber,as a complex carbohydrate that cannot be degraded by the host's di-gestive enzymes but can be utilized by gut microbiota,has biological functions that depend on its interaction with the gut microbiota.The metabolic products such as short-chain fatty acids produced by the fermentation of dietary fiber by gut microbiota can affect the host's intestinal health,body metabolism,reproduction,develop-ment,and aging process by regulating the function of the intestinal epithelial barrier,immune response,and metabolic pathways.At the same time,the digestive capacity and immune status of the animal host also affect the utilization efficiency of dietary fiber and the structure of the gut microbiota.The imbalance of the dynamic symbiotic network,such as insufficient dietary fiber or gut microbiota dysbiosis,can lead to metabolic disor-ders,inflammatory responses,and the occurrence of various diseases.This article systematically expounded the dynamic symbiotic network formed among dietary fiber,gut microbiota,and animal hosts through the mecha-nism of"substrate supply-metabolic regulation-environmental adaptation",and deeply analyzed the complex interaction pathways among dietary fiber,gut microbiota and animal hosts,in order to provide a theoretical ba-sis for animal nutrition regulation and intestinal health management.[Chinese Journal of Animal Nutrition,2026,38(4):2401-2415]
陈鹏;张春华;金鹿;孙海洲
内蒙古农业大学动物科学学院,呼和浩特 010018内蒙古自治区农牧业科学院,内蒙古自治区草食动物营养科学重点实验室,农业农村部草食家畜健康养殖与畜产品品质调控重点室(部省共建),呼和浩特 010031内蒙古自治区农牧业科学院,内蒙古自治区草食动物营养科学重点实验室,农业农村部草食家畜健康养殖与畜产品品质调控重点室(部省共建),呼和浩特 010031内蒙古农业大学动物科学学院,呼和浩特 010018||内蒙古自治区农牧业科学院,内蒙古自治区草食动物营养科学重点实验室,农业农村部草食家畜健康养殖与畜产品品质调控重点室(部省共建),呼和浩特 010031
农业科技
膳食纤维肠道微生物动物健康动态共生网络
dietary fibergut microbiotaanimal healthdynamic symbiotic network
《动物营养学报》 2026 (4)
2401-2415,15
国家重点研发计划(2022YFD1301102)"英才兴蒙"工程二层次团队(2025TEL18)国家草业技术创新中心(筹)重大创新平台建设专项(CCPTZX2023B06)国家绒毛用羊产业技术体系(CARS-39-11)内蒙古自治区草食动物营养科学重点实验室匹配资金项目(2025KYPT0080,2025KYPT0082)农业农村部草食家畜健康养殖与畜产品品质调控重点室(部省共建)匹配资金项目(2023CXJJM08)
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