Dioscorea bulbifera L.induces liver injury in mice partly through bile acids metabolic disorders and gut microbiota dysbiosis mediated by the YY1-FXR/Nrf2 signaling pathwayOA
Dioscorea bulbifera L.induces liver injury in mice partly through bile acids metabolic disorders and gut microbiota dysbiosis mediated by the YY1-FXR/Nrf2 signaling pathway
Bo-Shen Zhao;Cui-Cui Ren;Ji-Ping Liu;Yun-Dong Xie;Xin Wang;Yu-Han Zhang;Hong-Zhe Zhu;Lei-Lei Shi;Hui-Zi Shangguan;Ling Ding;Shu-Hong Zhu
Department of Pharmacology,Shaanxi University of Chinese Medicine,Xianyang 712046,ChinaDepartment of Pharmacy,First Hospital of Xi'an,Xi'an 710002,ChinaDepartment of Pharmacology,Shaanxi University of Chinese Medicine,Xianyang 712046,China||Key Laboratory of Pharmacodynamic Mechanism and Material Basis of Traditional Chinese Medicine,Shaanxi Administration of Traditional Chinese Medicine,Xianyang 712046,China||Engineering Research Center of Brain Health Industry of Chinese Medicine,Universities of Shaanxi Province,Xianyang 712046,ChinaDepartment of Pharmacology,Shaanxi University of Chinese Medicine,Xianyang 712046,ChinaDepartment of Pharmacology,Shaanxi University of Chinese Medicine,Xianyang 712046,ChinaDepartment of Pharmacology,Shaanxi University of Chinese Medicine,Xianyang 712046,ChinaDepartment of Pharmacology,Shaanxi University of Chinese Medicine,Xianyang 712046,ChinaDepartment of Pharmacology,Shaanxi University of Chinese Medicine,Xianyang 712046,ChinaDepartment of Pharmacology,Shaanxi University of Chinese Medicine,Xianyang 712046,ChinaDepartment of Pharmacology,Shaanxi University of Chinese Medicine,Xianyang 712046,ChinaDepartment of Pharmacy,First Hospital of Xi'an,Xi'an 710002,China
Dioscorea bulbifera L.liver injurybile acids metabolismgut microbiotashort-chain fatty acids
Dioscorea bulbifera L.liver injurybile acids metabolismgut microbiotashort-chain fatty acids
《传统医学研究（英文版）》 2026 (8)
15-27,13
This work was supported by the National Natural Science Foundation of China(82204790),Shaanxi University of Chinese Medicine Science and Technology Program(2024-LJRC-04),Shaanxi Province Natural Science Foundation(2024JC-YBMS-759),and Qinchuangyuan TCM Industry Innovation Project(L2024-QCY-ZYYJJQ-X29).Some cartoon elements were sourced from https://app.biorender.com.
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