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多模态影像技术在颈动脉粥样硬化疾病中的应用进展OA

Application and progress of multimodal imaging technology in carotid atherosclerotic disease

中文摘要英文摘要

动脉粥样硬化导致的缺血性卒中是全球致残和死亡的主要原因,而颈动脉粥样硬化作为引起缺血性卒中发作的主要原因之一,对其进行早期预防、诊断、评估以及治疗方式的选择尤为重要.目前,对颈动脉粥样硬化的研究已从传统的管腔狭窄评估,转向关注斑块易损性、血流动力学等综合风险分层.然而,先进技术的临床应用整合、标准化解读及其如何应用指导个体化治疗,仍缺乏系统性梳理.本文综述了颈动脉粥样硬化的多模态影像学评估、新型危险因素、斑块评分及外科治疗进展,重点介绍了高分辨率磁共振血管壁成像、计算流体力学和4D-flow MRI等先进影像技术在斑块成分分析、血流动力学评估和斑块风险分层中的应用,指出了目前相关研究在临床应用中的局限性并分析未来可行的研究方向.本文旨在整合多模态影像技术与个体化治疗策略,为相关研究指明新方向,助力实现该疾病的精准诊疗.

Ischemic stroke caused by atherosclerosis is a major cause of disability and death globally.Carotid atherosclerosis,as one of the primary causes of ischemic stroke episodes,is particularly important for early prevention,diagnosis,assessment,and selection of treatment methods.Currently,research on carotid atherosclerosis has shifted from traditional lumen stenosis assessment to focusing on comprehensive risk stratification,such as plaque vulnerability and hemodynamics.However,there is still a lack of systematic organization regarding the clinical application integration,standardized interpretation,and how to apply these technologies to guide individualized treatment.This article reviews the multimodal imaging assessment,novel risk factors,plaque scoring,and surgical treatment progress of carotid atherosclerosis.It focuses on the application of advanced imaging technologies,such as high-resolution magnetic resonance vascular wall imaging,computational fluid dynamics,and 4D-flow MRI,in plaque composition analysis,hemodynamic assessment,and plaque risk stratification.It also points out the limitations of current related research in clinical application and analyzes feasible future research directions.This article aims to integrate multimodal imaging technology with individualized treatment strategies,indicating new directions for related research and contributing to achieving precise diagnosis and treatment.

牛晶洁;高阳;吴琼;何金龙;王泽华;罗彤

内蒙古医科大学附属医院影像诊断科,呼和浩特 010050内蒙古医科大学附属医院影像诊断科,呼和浩特 010050内蒙古医科大学附属医院影像诊断科,呼和浩特 010050内蒙古医科大学附属医院影像诊断科,呼和浩特 010050内蒙古医科大学附属医院影像诊断科,呼和浩特 010050内蒙古医科大学附属医院影像诊断科,呼和浩特 010050

医药卫生

缺血性脑卒中颈动脉粥样硬化多模态影像技术高分辨率磁共振血管壁成像磁共振成像血流动力学

ischemic strokecarotid atherosclerosismultimodal imaging technologyhigh-resolution magnetic resonance vascular wall imagingmagnetic resonance imaginghemodynamics

《磁共振成像》 2026 (3)

174-180,7

Natural Science Foundation of Inner Mongolia(No.2023QN08055). 内蒙古自治区自然科学基金项目(编号:2023QN08055)

10.12015/issn.1674-8034.2026.03.025

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