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孟河医派特色治疗慢性阻塞性肺疾病OA

Menghe Medical School's distinctive treatment for chronic obstructive pulmonary disease

中文摘要英文摘要

目的 探讨孟河医派特色诊疗方案治疗慢性阻塞性肺疾病的临床疗效.方法 选择慢性阻塞性肺疾病患者240例,采用真实世界研究中的实用临床试验(PCT)设计方法,分为对照组与观察组,各120例.对照组单纯采用西医常规治疗,观察组在西医常规治疗基础上予病证型模式中医辨证治疗,比较2组各项临床指标变化.结果 与治疗前比较,治疗后2组CAT评分明显下降(P<0.05),观察组低于对照组(P<0.05);治疗后,2组咳嗽、咯痰、痰色、喘息等症状积分均有所下降,且观察组改善更明显(P<0.05);2组肺功能指标均明显改善,且观察组改善更明显(P<0.05);治疗后,与对照组比较,观察组血氧饱和度(SaO₂)、动脉血氧分压(PaO₂)提升更显著,动脉血二氧化碳分压(PaCO₂)降至更低水平(P<0.05).结论 孟河医派以"和法缓治、脾胃为本、痰瘀同治、综合干预"为核心的诊疗方案,能显著改善慢性阻塞性肺疾病患者临床症状、生理功能,有效降低急性加重频率.

Objective To explore the clinical efficacy of the Menghe Medical School's distinctive diagnosis and treatment protocol of chronic obstructive pulmonary disease(COPD).Methods 240 patients with COPD were selected and divided into the control group and the observation group,with 120 cases in each group,using the pragmatic clinical trial(PCT)design method from real-world reasearch.The control group received conventional Western medicine alone,while the observation group was given TCM treatment based on syndrome differentiation based on conventional Western medicine therapy.The Changes in clinical indicators were compared between two groups.Results Compared with before treatment,COPD Assessment Test(CAT)scores significantly decreased in both groups after treatment(P<0.05),and the observation group was lower than the control group(P<0.05).After treatment,symptom scores for cough,expectoration,sputum color,and wheezing decreased in both groups,and the observation group showed more significant improvement(P<0.05).Both groups showed significant improvement in pulmonary function indices,with the observation group demonstrating more pronounced improvement(P<0.05).After treatment,compared with the control group,the observation group showed more significant improvemet in blood oxygen saturation(SaO2)and arterial partial pressure of oxygen(PaO2),with arterial partial pressure of carbon dioxide(PaCO2)decreasing to the lower level(P<0.05).Conclusion The Menghe Medical School's treatment protocol,centered on"harmonizing therapy with gradual treatment,spleen and stomach as the foundation,simultaneous treatment of phlegm and stasis,and comprehensive intervention",can significantly alleviate clinical symptoms and improve physiological function in patients with COPD,while effectively reducing the frequency of acute exacerbations.

陈黎婷;许婷;顾楠;梅伟英;梅文星

常州市中医医院肺病科,江苏 常州 213000常州市中医医院肺病科,江苏 常州 213000常州市中医医院肺病科,江苏 常州 213000常州市中医医院肺病科,江苏 常州 213000常州市中医医院肺病科,江苏 常州 213000

医药卫生

孟河医派真实世界慢性阻塞性肺疾病脾胃为本

Menghe Medical Schoolreal-world studychronic obstructive pulmonary diseasespleen and stomach as the foundation

《长春中医药大学学报》 2026 (4)

467-472,6

江苏省科学技术计划项目(2023CFB432)2024常州市孟河医派传承创新发展项目(MH202405)

10.13463/j.cnki.cczyy.2026.04.018

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