基于"痞坚之处,必有伏阳"理论探讨三阴性乳腺癌OA
Discussion on triple-negative breast cancer based on the theory of"where there is mass hardness,there must be latent yang"
三阴性乳腺癌(TNBC)侵袭高性、复发转移风险高、预后差,缺乏明确靶点.基于《黄帝内经》中女子生理病理特点探析三阴性乳腺癌病因病机为阳明脉衰、阳气不足、肝肾精亏是发病核心条件,情志内伤、气机郁滞为体质因素,痰瘀并生、久蕴乳络是演变基础,伏阳化火、毒邪流窜是转移关键.基于"痞坚之处,必有伏阳"理论探讨三阴性乳腺癌防治思路,治以温阳化气、行气开郁、化痰散瘀、清热解毒、益气养血的治法.整合中医经典理论与现代医学机制,以期为临床治疗三阴性乳腺癌提供新思路.
Triple-negative breast cancer(TNBC)exhibits high invasiveness,elevated risk of recurrence and metastasis,and poor prognosis,and lacks clear therapeutic targets.Based on the analysis of women's physiological and pathological characteristics in the Yellow Emperor's Internal Classic,it is believed that the etiology and pathogenesis of TNBC are that Yangming meridian deficiency,insufficient yang energy,and deficiency of liver and kidney essence are the core conditions for the onset of the disease,emotional trauma and qi stagnation are constitutional factors,the concurrent generation of phlegm and stasis which persistently accumulate in the milk ducts is foundation for its progression,and latent yang transforming into fire and pathogenic toxins spreading throughout the body are key factors in metastasis.Based on the theory of"where there is mass hardness,there must be latent yang",this paper discusses the prevention and treatment ideas of TNBC,and the treatment methods include warming yang to transform qi,promoting qi circulation to resolve stagnation,resolving phlegm and dispersing stasis,clearing heat and detoxifying,and tonifying qi and nourishing blood.By integrating classical TCM theories with modern medical mechanisms,this study aims to provide novel insights for the clinical treatment of TNBC.
张文风;徐义丰;李楠;马源
长春中医药大学基础医学院,长春 130117长春中医药大学基础医学院,长春 130117长春中医药大学基础医学院,长春 130117长春中医药大学基础医学院,长春 130117
医药卫生
三阴性乳腺癌痞坚伏阳
triple-negative breast cancermass hardnesslatent yang
《长春中医药大学学报》 2026 (4)
383-387,5
吉林省中医药管理局项目-张文风名老中医专家传承工作室(吉中医药发[2023]56号)长春市科学技术局高校院所中试遴选项目(24GXYSZZ16)
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