首页|期刊导航|滨州医学院学报|冠状动脉粥样硬化性心脏病发病的危险因素

冠状动脉粥样硬化性心脏病发病的危险因素OA

Risk factors for coronary heart disease

中文摘要英文摘要

目的 综合评价冠状动脉粥样硬化性心脏病发病的主要危险因素,为疾病预防提供医学循证依据.方法 系统检索中国知网、万方数据知识服务平台、中国生物医学文献服务系统(SinoMe)、维普资讯、PubMed、the Cochrane Librar-y、Web of Science和Embase数据库中有关冠状动脉粥样硬化性心脏病发病危险因素研究的文献,收集建库至 2025 年 5月发表的相关研究.应用美国卫生保健质量研究局工具和纽卡斯尔-渥太华量表进行质量评估,采用RevMan 5.4 和StateMP1 7 软件进行Meta分析.结果 冠状动脉粥样硬化心脏病危险因素包括男性、年龄、吸烟、高血压病史、糖尿病病史、高脂血症、冠状动脉粥样硬化性心脏病家族史、甘油三酯、高密度脂蛋白胆固醇降低、低密度脂蛋白胆固醇升高、体质量指数、睡眠<7 h、缺乏体育锻炼.结论 冠状动脉粥样硬化性心脏病发病的危险因素可分为不可改变和可改变两类,临床工作者应当聚焦可调控因素,早期实施针对性干预方案,从而显著降低冠状动脉粥样硬化性心脏病发生率.

Objective To comprehensively evaluate the main risk factors for coronary heart disease and provide medical evi-dence-based basis for disease prevention.Methods Systematic searches were conducted for literatures on the risk factors of coro-nary heart disease in China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Platform(WanFang Data-base),China Biomedical Literature Service System(SinoMed),VIP,PubMed,the Cochrane Library,Web of Science(WOS),and Embase databases to collect relevant studies published until May 2025.The American Health Quality Research Service(AHRQ)tools and the Newcastle Ottawa Scale(NOS)were used for quality assessment,and RevMan 5.4 and State MP1 7 soft-ware were used for meta-analysis.Results Risk factors of coronary atherosclerotic heart disease include:male,smoking,hyper-tension,diabetes,hyperlipidemia,family history of coronary heart disease,triglyceride,low level HDL-C,high level LDL-C,BMI,sleep less than 7 hours,and the lack of physical exercises.Conclusion The risk factors for coronary heart disease can be divided into two categories:unchangeable and modifiable.Clinical workers should focus on modifiable factors and implement tar-geted intervention plans in the early stages to significantly reduce the incidence of the disease.

纪丽君;张海莲

延边大学护理学院 吉林 延边朝鲜族自治州 1 33000延边大学护理学院 吉林 延边朝鲜族自治州 1 33000

医药卫生

高危人群冠状动脉粥样硬化性心脏病危险因素meta分析

high risk populationcoronary heart diseaserisk factormeta-analysis

《滨州医学院学报》 2026 (2)

159-164,6

10.19739/j.cnki.issn1001-9510.2026.02.008

评论