从"浊邪害清"论治持续性姿势-知觉性头晕OA
Treating persistent postural-perceptual dizziness based on the"turbid pathogen disturbing clearness"theory
持续性姿势-知觉性头晕具有患病率高、病因病机复杂、病程缠绵、常伴有焦虑抑郁情绪等特点,病位在脑,病机以虚实夹杂为主,病变多涉及脾、肝、肾三脏.因其发病机制尚不明确,目前治疗缺乏特异性疗法."浊邪害清"理论源自《温热论》,总结了湿热浊邪上蒙清窍的致病规律.基于此,本文提出持续性姿势-知觉性头晕的主要病因,多由饮食不节、情绪失调、年老久病等因素所导致脾、肝、肾三脏功能失调,进而湿浊、痰浊、瘀浊等浊邪内生;核心病机在于浊邪蒙蔽清窍、扰乱清阳,导致清窍不利、元神失司.治疗上,依据浊邪的演变过程分为浊邪初生期、浊邪壅盛期、浊邪深伏期三期辨治,确立了以调理脏腑、祛浊通窍、扶正固本为核心的分期治疗原则.浊邪初生期,治以健脾、疏肝、温肾,以杜绝浊邪产生;浊邪壅盛期,治以化痰、祛湿、逐瘀,以复清窍之通利;浊邪深伏期,治以补气醒脑,以扶助正气,祛除深伏之浊邪.临证用药时,可根据浊邪演变进程及证候特点灵活加减化裁.应用"浊邪害清"理论指导持续性姿势-知觉性头晕的治疗,可为中医药诊疗该疾病提供新思路与实践依据.
Persistent postural-perceptual dizziness(PPPD)is typically characterized by high prevalence,a complex etiology and pathogenesis,and a prolonged disease course.It is also frequently associated with anxiety and depression.PPPD originates in the brain,with its pathogenesis primarily characterized by a deficiency-excess complex.Its onset often involves the spleen,liver,and kidney.Western medical treatment lacks specific therapeutic approaches owing to its unclear pathogenesis.The"turbid pathogen disturbing clearness"theory,which summarizes the pathogenic pattern of dampness-heat turbid pathogen clouding the clear orifices,is derived from the Wenre Lun.From this perspective,the paper hypothesizes that the causative factors of PPPD involve dysfunction of the spleen,liver,and kidney owing to irregular diet,emotional disturbances,aging,and chronic illness,which leads to the internal generation of turbid pathogens such as dampness-turbidity,phlegm-turbidity,and blood stasis turbidity.The core pathogenesis is that turbid pathogens obscure the clear orifices and disturb the clear yang,leading to dysfunction of the clear orifices and to the failure of the original spirit to govern.Based on the pathological progression of the turbid pathogen,the disease is treated in three stages:incipient,exuberant,and latent.The principle of phased treatment centers on regulating the zang-fu,expelling turbid pathogens,unblocking orifices,and strengthening the body's foundations.During the incipient stage,therapy focuses on strengthening the spleen,soothing the liver,and warming the kidney to prevent the generation of turbid pathogen;during the exuberant stage,therapy emphasizes resolving phlegm,dispelling dampness,and eliminating blood stasis to restore the function of the clear orifices;during the latent stage,therapy focuses on tonifying qi and clearing the mind to support vital qi and expel the latent turbid pathogen.During clinical management,adjustments can be made based on the progression of the turbid pathogen and the characteristics of the syndrome.Using the"turbid pathogen disturbing clearness"theory to guide the treatment of PPPD can provide new perspectives and practical guidance for its clinical diagnosis and treatment in traditional Chinese medicine.
张雨琪;张秉睿;杜雅薇;吴圣贤
北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700
医药卫生
持续性姿势-知觉性头晕浊邪清窍清阳
persistent postural-perceptual dizzinessturbid pathogenclear orificesclear yang
《北京中医药大学学报》 2026 (4)
557-564,8
国家自然科学基金面上项目(No.82174340) National Natural Science Foundation of China General Program(No.82174340)
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