不同时序针灸结合康复机器人步态训练治疗帕金森病的临床研究OA

Objective:To explore the clinical efficacy of different temporal sequences of acupuncture combined with rehabilitation robot-assisted gait training(RAGT)in the treatment of Parkinson's disease(PD).Methods:Sixty PD patients were randomly divided into a control group(30 cases)and an observation group(30 cases).The control group received RAGT after acupuncture at Baihui(GV20)and Dazhui(GV14),while the observation group received RAGT simultaneously with acupuncture.Both groups were treated for 12 consecutive weeks.The Unified Parkinson's Disease Rating Scale(UPDRS)score,6-minute walk test(6MWT)distance,and 39-item Parkinson's Disease Questionnaire(PDQ-39)score were evaluated in the two groups before treatment,at the 4th week,the 8th week,and the 12th week.Results:After 8 and 12 weeks of treatment,the total UPDRS score of the control group was significantly lower than that before treatment(P<0.05).The improvement was mainly due to the decrease in the UPDRS-III scale score,while the UPDRS-I,II,and IV scores showed no significant changes(P>0.05).The total UPDRS score of the observation group was significantly lower than that before treatment at each time point(P<0.05),and the improvement range covered the UPDRS-I,II,and III scores.In addition,compared with before treatment,the 6MWT distance was increased and the PDQ-39 score was decreased in both groups at each time point(P<0.05).At the 8th and 12th weeks of treatment,the UPDRS-III score of the observation group was significantly lower than that of the control group(P<0.05);at the 12th week of treatment,the total UPDRS score of the observation group was also significantly lower than that of the control group(P<0.05).However,there was no statistically significant difference in the 6MWT distance and PDQ-39 score between the two groups at each time point(P>0.05).Conclusion:Acupuncture at Baihui(GV20)and Dazhui(GV14)combined with RAGT can effectively improve the UPDRS score,walking ability,and quality of life of PD patients.Compared with acupuncture first followed by rehabilitation training,synchronous training with needle retention has a better long-term effect in improving the motor function of patients.