快速镇静联合认知唤醒疗法在老年期痴呆患者急诊躁动处置中的应用研究OA
Application of rapid sedation combined with cognitive arousal therapy in the treatment of agitation in emergency department patients with dementia
目的:探讨在老年期痴呆患者急诊躁动处置中快速镇静联合认知唤醒疗法的应用效果.方法:选取 2023 年 1月至 2025 年 12 月医院急诊入院的 115 例接受治疗的老年期痴呆患者为研究对象,采用随机数字表法分成对照组和试验组,对照组 57 例采用急诊躁动处置,试验组 58 例采用快速镇静联合认知唤醒疗法,比较两组的控制总有效率、镇静起效时间、谵妄评估量表(CAM)评分、急诊处置总依从率.结果:试验组躁动控制总有效率为 94.83%,高于对照组的 80.70%,差异有统计学意义(P＜0.05).试验组患者与对照组比较,镇静起效时间更快、镇静持续时间更长,差异有统计学意义(P＜0.05).试验组患者干预 24 h 后与对照组比较,谵妄评估量表(CAM)评分显著更低(P＜0.05).试验组患者急诊处置总依从率为93.10%,高于对照组的 77.19%,差异有统计学意义(P＜0.05).试验组患者不良反应率为 6.90%,低于对照组的 21.05%,差异有统计学意义(P＜0.05).结论:老年期痴呆患者急诊躁动处置过程中将快速镇静与认知唤醒疗法相结合,能快速且持续镇静,让患者保持良好的依从性,提高病情控制效果.
Objective:To explore the application effect of rapid sedation combined with Cognitive Arousal Therapy in the emergency treatment of agitation in Alzheimer's disease patients.Methods:A total of 115 Alzheimer's disease patients admitted to our hospital from January 2023 to December 2025 were selected as subjects and randomly divided into a conventional group and an experimental group using a random number table method.The conventional emergency agitation treatment was administered to 57 cases in the conventional group,while rapid sedation combined with cognitive awakening therapy was applied to 58 cases in the experimental group.The intervention outcomes were compared.Results:The total effective rate of agitation control in the experimental group was 94.83%,significantly higher than that in the conventional group(80.70%),with a statistically significant difference(P<0.05).Compared with the conventional group,the experimental group exhibited faster onset of sedation and longer duration of sedation,with a statistically significant difference(P<0.05).At 24 hours post-intervention,the Confusion Assessment Method(CAM)scores were significantly lower in the experimental group than in the conventional group(P<0.05).The overall compliance rate in the experimental group was 93.10%,significantly higher than that in the conventional group(77.19%),with a statistically significant difference(P<0.05).The adverse reaction rate in the experimental group was 6.90%,significantly lower than that in the conventional group(21.05%),with a statistically significant difference(P<0.05).Conclusion:Combining rapid sedation with cognitive awakening therapy in the emergency treatment of agitation in Alzheimer's disease patients can achieve rapid and sustained sedation,maintain good compliance,and improve disease control effectiveness.
郭科;贺利宁;何振;杨蕙萍
苏州大学附属常州老年病医院(常州市第七人民医院),江苏 苏州 213000苏州大学附属常州老年病医院(常州市第七人民医院),江苏 苏州 213000苏州大学附属常州老年病医院(常州市第七人民医院),江苏 苏州 213000苏州大学附属常州老年病医院(常州市第七人民医院),江苏 苏州 213000
医药卫生
快速镇静认知唤醒疗法老年期痴呆急诊躁动
Rapid sedationCognitive arousal therapyDementia in elderlyEmergencyRestlessness
《阿尔茨海默病及相关病》 2026 (2)
90-95,6
江苏省医院协会、江苏现代医院管理研究中心、医院管理创新研究课题(JSYGY-3-2025-267)
评论