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动物源性食品中兽药残留危害及常用检测方法OA

Hazards and common detection methods of veterinary drug residues in animal derived food

中文摘要英文摘要

动物养殖过程中违规使用兽药,易造成动物产品药物残留,进而可能引发食品安全风险、危害公众健康及破坏生态平衡.本文系统综述了动物源性食品安全风险监测中常见药物残留的种类及危害,并介绍了常用检测技术.本文列举的养殖生产中主要残留药物检测种类包括β-受体激动剂类、氯霉素、金刚烷胺、硝基呋喃类药物、孔雀石绿等禁用药物,以及磺胺类、喹诺酮类、酰胺醇类及代谢物、四环素类、地西泮和地塞米松等停用、限用药物;食用上述药物残留的动物源性食品可能会造成消化系统不适(恶心、食欲减退),肝脏、肾脏等损伤,危害公众健康.生产中常使用酶联免疫吸附法、胶体金法进行初筛,同时辅以高效液相色谱法、高效液相色谱—串联质谱法进行结果验证,多方法协同作用可提高检测的准确性.本文为动物源性食品安全监管提供参考.

Illegal use of veterinary drugs during animal breeding easily leads to drug residues in animal products,which in turn triggers food safety risks,endangers public health,and disrupts ecological balance.This paper systematically reviewed the categories and hazards of common drug residues in food safety risk monitoring of animal derived foods,and introduced commonly used detection technologies.This paper lists the main residual veterinary drugs detected in breeding and production,including prohibited drugs such as β-agonists,chloramphenicol,amantadine,nitrofuran derivatives,malachite green,as well as restricted or suspended-use drugs including sulfonamides,quinolones,amphenicols and their metabolites,tetracyclines,diazepam and dexamethasone.Consumption of animal derived foods containing residues of the above-mentioned drugs may cause digestive discomfort(nausea,loss of appetite),as well as damage to the liver,kidneys and other organs,posing a threat to public health.In production,enzyme-linked immunosorbent assay(ELISA)and colloidal gold assay are often used for preliminary screening,supplemented by high-performance liquid chromatography(HPLC)and high-performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS)for result verification.The synergistic application of multiple methods can improve the accuracy of detection.This paper provides a reference for food safety supervision of animal-derived foods.

张苏珍;贺燕;王益军;陶威;田蕴;葛敏;张竞男

连云港市畜产品质量监督检验测试中心,江苏 连云港 222000连云港市畜产品质量监督检验测试中心,江苏 连云港 222000连云港市畜产品质量监督检验测试中心,江苏 连云港 222000连云港市畜产品质量监督检验测试中心,江苏 连云港 222000连云港市畜产品质量监督检验测试中心,江苏 连云港 222000连云港市畜产品质量监督检验测试中心,江苏 连云港 222000连云港市畜产品质量监督检验测试中心,江苏 连云港 222000

轻工纺织

动物源性食品兽药残留药物危害检测方法

animal derived foodveterinary drug residuesdrug hazardsdetection methods

《安徽农学通报》 2026 (8)

42-46,5

10.16377/j.cnki.issn1007-7731.2026.08.011

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