A cohort study on the A8G6 neutralizing antibody intranasal spray for preventing SARS-CoV-2 infection in healthcare workersOA
SARS-CoV-2 has evolved dramatically since the COVID-19 pandemic in Dec 2019,acquiring mutations that enhance transmissibility,infectivity,and immune evasion.1 Unlike other variants targeting lungs,Omicron altered entry pathways and promoted replication in the upper respiratory tract,resulting in more asymptomatic cases.This facilitated its spread and posed challenges to infection prevention.
Shu Zhang;Zhigang Chu;Siyuan Yang;Qiuling Shi;Qinghua Zhao;Dawei He;Hongmei Xu;Dan Zhang;Zhu Yang;Ailong Huang
The First Affiliated Hospital of Chongqing Medical University,Chongqing 400013,ChinaThe First Affiliated Hospital of Chongqing Medical University,Chongqing 400013,ChinaChongqing Medical University,Chongqing 400013,ChinaChongqing Medical University,Chongqing 400013,ChinaThe First Affiliated Hospital of Chongqing Medical University,Chongqing 400013,ChinaThe Second Affiliated Hospital of Chongqing Medical University,Chongqing 400013,ChinaChildren''s Hospital of Chongqing Medical University,Chongqing 400013,ChinaThe First Affiliated Hospital of Chongqing Medical University,Chongqing 400013,ChinaChongqing Medical University,Chongqing 400013,ChinaChongqing Medical University,Chongqing 400013,China
医药卫生
Healthcare workersMutationsViral evolutionCohort studySARS CoV infectionentry pathwaysIntranasal sprayG neutralizing antibody
《Genes & Diseases》 2026 (2)
P.10-12,3
supported by the Science and Technology Innovation Key R&D Program of Chongqing,China(No.CSTB2022TIAD-STX0013).
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