Electrochemical difunctionalization of isocyanides by a three-component reaction cascade Mumm rearrangement:Rapid access to sulfur-containing imidesOA
An efficient and practical electrochemical method for the three-component reaction cascade Mumm rearrangement of imides has been developed using a simple undivided cell with carbon electrodes at room temperature,which provides a useful strategy for the rapid synthesis of sulfur-containing imides with broad substrate scope and high functional tolerance.It is a rare example of in situ generation of O-acyl isoamide precursor for Mumm rearrangement.
Hongmei Jiang;Zhibin Nong;Xi Chen;Tiancheng Cai;Hanxuan Zhang;Rui Li;Qiang Li;Lei Liu;Qing-Wen Gui
College of Chemistry and Materials Science,Hunan Agricultural University,Changsha 410128,China College of Agronomy,Hunan Agricultural University,Changsha 410128,ChinaCollege of Chemistry and Materials Science,Hunan Agricultural University,Changsha 410128,ChinaCollege of Chemistry and Materials Science,Hunan Agricultural University,Changsha 410128,ChinaCollege of Chemistry and Materials Science,Hunan Agricultural University,Changsha 410128,ChinaCollege of Chemistry and Materials Science,Hunan Agricultural University,Changsha 410128,ChinaCollege of Chemistry and Materials Science,Hunan Agricultural University,Changsha 410128,ChinaCollege of Chemistry and Materials Science,Hunan Agricultural University,Changsha 410128,China College of Agronomy,Hunan Agricultural University,Changsha 410128,ChinaCollege of Chemistry and Materials Science,Hunan Agricultural University,Changsha 410128,ChinaCollege of Chemistry and Materials Science,Hunan Agricultural University,Changsha 410128,China
化学化工
Electrochemical difunctionalizationCascade Mumm rearrangementThree-component reactionSulfur-containing imidesO-acyl isoamide
《Green Synthesis and Catalysis》 2026 (1)
P.119-123,5
support from the Science and Technology Innovation Program of Hunan Province(No.2021RC2079)China Postdoctoral Science Foundation(Nos.2022T150075 and 2022M720541)Hunan Provincial Department of Education Outstanding Youth Project(No.22B0212)Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(No.TSBI-CIP-CXRC-038)National College Students Innovation and Entrepreneurship Training Program(No.S202210537024).
评论