β-Galactosidase Based Molecular Imaging for Visualization of Cellular SenescenceOA
Cellular senescence is a distinct and irreversible biological process characterized by cell cycle arrest.It can be triggered by various stressors,including DNA damage,oxidative stress,telomere dysfunction,oncogenic activation,or extensive replication as well as by physiological stimuli such as developmental and repair signals[1].
Jiani Huang;Peili Cen;Hong Zhang;Yan Zhong
Department of Nuclear Medicine,Zhejiang Cancer Hospital,Hangzhou Institute of Medicine,Chinese Academy of Sciences,Hangzhou,China Department of Nuclear Medicine and PET Center,The Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou,China Institute of Nuclear Medicine and Molecular Imaging of Zhejiang University,Hangzhou,China Key Laboratory of Medical Molecular Imaging of Zhejiang Province,Hangzhou,ChinaDepartment of Nuclear Medicine,Zhejiang Cancer Hospital,Hangzhou Institute of Medicine,Chinese Academy of Sciences,Hangzhou,China Department of Nuclear Medicine and PET Center,The Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou,China Institute of Nuclear Medicine and Molecular Imaging of Zhejiang University,Hangzhou,China Key Laboratory of Medical Molecular Imaging of Zhejiang Province,Hangzhou,ChinaDepartment of Nuclear Medicine,Zhejiang Cancer Hospital,Hangzhou Institute of Medicine,Chinese Academy of Sciences,Hangzhou,China Institute of Nuclear Medicine and Molecular Imaging of Zhejiang University,Hangzhou,China Key Laboratory of Medical Molecular Imaging of Zhejiang Province,Hangzhou,ChinaDepartment of Nuclear Medicine,Zhejiang Cancer Hospital,Hangzhou Institute of Medicine,Chinese Academy of Sciences,Hangzhou,China Institute of Nuclear Medicine and Molecular Imaging of Zhejiang University,Hangzhou,China Key Laboratory of Medical Molecular Imaging of Zhejiang Province,Hangzhou,China
医药卫生
cellular senescencemolecular imagingsenescence-associatedβ-galactosidase
《iRADIOLOGY》 2026 (1)
P.63-65,3
supported by the National Key Research and Development Program of China(2021YFA1101700)the National Natural Science Foundation of China(82394433,82361148130,82302262)the Zhejiang Provincial Natural Science Foundation of China(LMS25H180002)the Postdoctoral Fellowship Program of CPSF(GZC20251313)the Fundamental Research Funds for the Central Universities(226-2024-00059).
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