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基于数据挖掘的何世东教授治疗失眠的用药规律分析OA

An analysis on the medication rules of Professor HE Shidong in the treatment of insomnia based on data mining

中文摘要英文摘要

目的:利用数据挖掘方法探索何世东教授治疗失眠患者的用药规律和经验,为中医药治疗失眠提供借鉴.方法:通过 R 语言、SPSS 软件及 Gephi 软件归纳与分析何世东教授 2023 年 5 月―2024 年 2 月在广州中医药大学东莞医院治疗失眠的内服方,采用中药关联规则、中药复杂网络分析和系统聚类等统计方法进行数据挖掘和分析,总结药物使用频次、功效类别、药性、药味、归经等,探讨失眠的诊治规律和常用方药.结果:研究结果显示,共有108 份病历纳入分析,使用频次较高的药物有茯苓、甘草、半夏、白芍、白术等,主要功效类别为补虚、安神、利水渗湿、清热等,药性多为平、寒、温,五味多为甘、苦、辛,归经多入脾经、肝经,常用药对为茯苓-甘草、半夏-茯苓等,核心处方为茯苓、甘草、半夏、白芍、太子参、酸枣仁、首乌藤、白术,并总结出5组常用组方.结论:何世东教授治疗失眠的用药重视所病脏腑及气血阴阳,调其寒热,从五脏归经论治,尤重肝脾同治,善用四逆散、半夏泻心汤、归脾汤等治疗肝脾不和、阴虚阳亢、寒热错杂、痰热扰心、脾肾两虚等所致的失眠.

Objective:This study aims to explore the medication rules and experience of Professor HE Shidong in the treatment of insomnia cases,and to provide scientific support for the treatment of insomnia by traditional Chinese medicine(TCM).Methods:Through R language,SPSS software and Gephi software,the oral formula of Professor he shidong for insomnia in Dongguan Hospital of Guangzhou University of Traditional Chinese Medicine from May 2023 to February 2024 was summarized and analyzed.Data mining and analysis were carried out by using statistical methods such as association rules,visualization of complex network analysis of TCM and system clustering.Data such as drug use frequency,category,drug natures,drug flavors and meridian tropisms were summarized,and the diagnosis and treatment rules and commonly used prescriptions of insomnia were compiled.Results:A total of 108 medical records were included in the analysis,and the drugs used frequently were Fu Ling(Poria),Gan Cao(Radix Glycyrrhizae),Ban Xia(Rhizoma Pinelliae),etc.The main categories were tonic drugs,sedative drugs,diuretic drugs,etc.The medicinal natures were mostly neutral,warm and cold.Most of the five flavors were sweet,bitter and pungent,and the meridian tropism was mostly of the spleen and liver meridians.The commonly used couplet medicinals were:Fu Ling-Gan Cao,Ban Xia-Fu Ling,among others.The core prescriptions were Fu Ling,Gan Cao,Ban Xia,etc.,and five groups of commonly used prescriptions were summarized.Conclusion:Professor HE Shidong emphasizes the regulation of the viscera,Qi(气),blood,Yin(阴)and Yang(阳),and regulates the cold and heat in the treatment of insomnia.In terms of medication,he addresses insomnia caused by disharmony between the liver and spleen,Yin deficiency and Yang hyperactivity,etc.,from the perspectives of five Zang(五脏)organs and meridian tropisms,with particular emphasis on liver and spleen harmony,and made full use of the Sini San(四逆散)and the Banxia Xiexin decoction(半夏泻心汤),etc.

尹婉君;谭静

广州中医药大学东莞医院,广东 东莞,523000广州中医药大学东莞医院,广东 东莞,523000

医药卫生

失眠数据挖掘规律分析

InsomniaData miningRegularity analysis

《中医临床研究》 2026 (1)

48-55,8

东莞市社会科技发展重点项目(202050715002182).

10.3969/j.issn.1674-7860.2026.01.007

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