沙棘酚类化合物化学组成及其生物活性研究进展OA
Research progress on chemical composition and bioactivity of Hippophae rhamnoides L.phenolic compounds
沙棘为药食同源植物,其功能活性主要源于富含沙棘酚类化合物(Hippophae rhamnoides L.Phenolic Compounds,HRPC).基于 HRPC 的结构特征,梳理了 164 种 HRPC 的化学组成及其在不同品系、不同植株部位的分布规律,并阐述了其8 种主要生物活性作用机制.HRPC 以黄酮类、酚酸类和单宁类化合物为主,其中黄酮类化合物数量多达117 种,具有抗氧化、抗炎、抗肿瘤、抗动脉粥样硬化、护胃、抗肺纤维化、抑制肥胖、调节肠道微生物群等多重生物活性.基于 HRPC 种类与含量、分布情况、生物活性机制和生物利用度现状,未来研究可聚焦在生物活性机制深度挖掘、加工方法革新、包裹体系优化等方面,以实现 HRPC 的高值化开发与沙棘产业升级.
Hippophae rhamnoides L.is a medicine-and-food homologous plant,and its functional activities mainly stem from its abundant phenolic compounds(HRPC).Based on the structural characteristics of HRPC,this review summarizes the chemical composition of 164 types of HRPCs and their distribution in different strains and plant parts,while highlighting the elucidation of their eight major bioactivity mechanisms.HRPCs are dominated by flavonoids,phenolic acids,and tannins.Among these,flavonoids constitute the main component with 117 identified types,which possess multiple bioactivities such as antioxidation,anti-inflammation,anti-tumorigenesis,anti-atherosclerosis,gastroprotection,anti-pulmonary fibrosis,anti-obesity,and gut microbiota modulation.Given the current status of HRPC species,content,distribution,bioactivity mechanisms,and bioavailability,future studies are recommended to focus on the in-depth exploration of bioactivity mechanisms,innovation of processing method,and optimization of encapsulation systems,thereby realizing the high-value utilization of HRPCs and the upgrading of the Hippophae rhamnoides L.industry.
申迎宾;邓玮亮;陈小乐;陈坤锥;李勇;张永;张磊
广州大学 生命科学学院,广东 广州 510006广州大学 生命科学学院,广东 广州 510006广州大学 生命科学学院,广东 广州 510006广州大学 生命科学学院,广东 广州 510006喀什慕峰酒业有限责任公司 科研部,新疆 喀什 844100喀什慕峰酒业有限责任公司 科研部,新疆 喀什 844100新疆农业大学 林学与风景园林学院,新疆 乌鲁木齐 830052
轻工纺织
沙棘酚类化合物化学组成生物活性
Hippophae rhamnoides L.phenolic compoundschemical compositionbioactivity
《轻工学报》 2026 (2)
1-20,20
新疆维吾尔自治区乡村振兴产业发展科技行动项目(2024NC008)广东省科学技术协会项目(KPXD20241105)
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