2019-2024年甘肃省天水市鸡高致病性禽流感免疫效果分析OA

In order to assess the immune efficacy against subtypes H5 and H7 of highly pathogenic avian influenza(HPAI)in chickens in Tianshui City,Gansu Province,blood samples were randomly collected from chickens in intensive farms and smallholders across 2 districts and 5 counties during 3-4 weeks following centralized spring and autumn vaccination campaigns from 2019 to 2024,to detect immune antibodies against the two subtypes using hemagglutination and hemagglutination inhibition test(HA-HI),followed by statistical comparison based on the results by year,region,season and farming mode.The results showed that annual average qualification rates of antibodies against subtypes H5 and H7 were above 70％,exceeding the standard(70％)required by the Ministry of Agriculture and Rural Affairs.Statistical significance was observed in the qualification rates in different years and regions(P＜0.01),rather than in different seasons and farming modes(P＞0.05).In conclusion,the immune efficacy against HPAI in chickens in the city was effective,remaining high level of immune antibodies in the flocks in different seasons and under different farming scales,and indicating a low risk of wide transmission of HPAI outbreaks.Nevertheless,HPAI vaccination and monitoring,as well as biosecurity regulation for farms/households should be continuously improved to avoid any sporadic outbreaks.