头孢比罗酯钠在耐甲氧西林金黄色葡萄球菌血流感染中应用的研究进展OA

Blood stream infection induced by multi-drug resistant bacteria is still one of the global public health problems with high incidence rate and mortality.Ceftobiprole medocaril sodium is the fifth generation cephalosporin,which has activity against various Gram-positive including methicillin resistant Staphylococcus aureus and Gram-negative bacteria.Ceftobiprole medocaril sodium is a potential drug for treatment of complex and potentially drug-resistant infections.This article reviews the mechanism of action,antibacterial activity,and clinical application of ceftobiprole medocaril sodium in blood stream infections induced by methicillin resistant S.aureus,providing reference for rational selection and use in clinical practice.