血栓弹力图在妊娠期糖尿病孕妇凝血状态监测中的应用价值OA
Application Value of Thrombelastogram in Monitoring Coagulation Status in Pregnant Women with Gestational Diabetes Mellitus
目的:探讨血栓弹力图(TEG)监测妊娠期糖尿病(GDM)孕妇凝血状态的价值.方法:选取 2023 年 6 月—2025 年 4 月于景德镇市第一人民医院就诊的GDM孕妇 40 例作为观察组,另纳入同期于本院产检的健康孕妇 40 例作为对照组.两组均进行传统凝血功能及TEG检测.比较两组TEG指标[凝血反应时间(R值)、凝血形成时间(K值)、凝血形成速率角(α角)、最大振幅(MA值)、凝血综合指数(CI值)]及传统凝血功能指标(PT、APTT、FIB、D-D),并分析TEG指标与凝血功能指标的相关性.结果:观察组FIB水平较对照组高(P<0.05);两组PT、APTT、D-D水平比较,差异无统计学意义(P>0.05).观察组R值、K值较对照组短,α角、MA值较对照组大,CI值较对照组高(P<0.05).Pearson相关性分析显示,R值与D-D呈负相关,CI值与D-D呈正相关(P<0.05).结论:TEG能更敏感的整体反映GDM孕妇的凝血状态.
Objective:To explore the value of thromboelastography(TEG)in monitoring the coagulation status in pregnant women with gestational diabetes mellitus(GDM).Method:Forty pregnant women with GDM who visited the First People's Hospital of Jingdezhen from June 2023 to April 2025 were selected as the observation group,and another 40 healthy pregnant women who underwent prenatal examinations at the same hospital during the same period were included as the control group.Both groups underwent traditional coagulation function and TEG examinations.The TEG indexes[coagulation reaction time(R value),coagulation formation time(K value),coagulation formation rate angle(α angle),maximum amplitude(MA value)and coagulation comprehensive index(CI value)]and traditional coagulation function indexes(PT,APTT,FIB,D-D)were compared between the two groups,and the correlation between TEG indexes and coagulation function indexes were analyzed.Result:The FIB levels in the observation group was higher than that in the control group(P<0.05).There were no statistically significant differences in the levels of PT,APTT,and D-D between the two groups(P>0.05).The R value and K value of the observation group were shorter than those of the control group,the α angle and MA value were larger than those of the control group,and the CI value was higher than that of the control group(P<0.05).Pearson correlation analysis showed that the R value was negatively correlated with D-D,the CI value was positively correlated with D-D(P<0.05).Conclusion:TEG can more sensitively and comprehensively reflect the coagulation status of pregnant women with GDM.
王金静;杨象斌;熊振;余萍
景德镇市第一人民医院输血科 江西 景德镇 333000景德镇市第一人民医院输血科 江西 景德镇 333000景德镇市妇幼保健院检验科 江西 景德镇 333000景德镇市第一人民医院检验科 江西 景德镇 333000
血栓弹力图妊娠期糖尿病凝血状态
ThromboelastographyGestational diabetes mellitusCoagulation status
《中国医学创新》 2026 (9)
116-120,5
景德镇市科技计划项目(20241SFZC003)
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