Klippel-Trenaunay综合征伴消化道出血的临床特征分析OA

[Objective]To investigate the clinical characteristics of a child with Klippel-Trenaunay syndrome(KTS)complicated by lower gastrointestinal bleeding,for better understanding of this rare condition.[Methods]A retrospective analysis was conducted on the clinical data of a pediatric KTS case with lower gastrointestinal bleeding admitted to the Department of Gastroenterology of the Affiliated Women and Children's Medical Center of Guangzhou Medical University in October 2024.Using"Klippel-Trenaunay Syndrome""KTS""Gastrointestinal Bleeding"as keywords,we searched for relevant literature in the Wanfang Chinese Database and PubMed database up to March 2025 in our analysis.[Results]The 8-year-old boy was admitted with a 4-year history of hematochezia that had worsened over the previous two weeks.He had been previously diagnosed with KTS in outpatient consultation for lower limb asymmetry.Gastrointestinal endoscopy revealed diffuse,tortuous,bluish-purple vessels in the mucosa from the sigmoid colon to the distal rectum.Oral polyethylene glycol and thalidomide significantly improved his hematochezia during follow-up.[Conclusion]KTS often involves multiple systems in children,requiring multidisciplinary collaboration.Comprehensive diagnostic procedures such as gastrointestinal endoscopy are essential for formulating individualized treatment plans.Thalidomide may play an active role in managing vascular malformations in the intestine,offering a promising therapeutic approach.