基于年龄-体质-证型关联的无症状肾性血尿群体辨证论治OA

For a long time,simple asymptomatic renal hematuria has not been taken seriously.Current studies have confirmed that renal hematuria is a risk factor for the progression of renal function,but there is no effective treatment available.Because asymptomatic renal hematuria is highly concealed and lacks typical symptoms,individualized syndrome differentiation in traditional Chinese medicine(TCM)is difficult,making it a challenge in clinical diagnosis and treatment.Although TCM has a long history and solid theoretical basis in the treatment of hematuria,it urgently needs to break through the bottleneck of traditional syndrome differentiation.Based on classical TCM theories,research achievements in modern constitution studies,and relevant clinical and pathological evidence,this article focuses on the decisive influence of age on constitution distribution and its regular association with the evolution of core syndromes,and constructs a three-dimensional diagnostic and therapeutic system of"age-constitution-syndrome".It reveals that the syndrome manifestations of asymptomatic renal hematuria are profoundly shaped by constitution,and that constitution shows a group distribution pattern with age-children often present with deficiency of lung and spleen Qi combined with wind-heat,young and middle-aged individuals often present with deficiency of liver and kidney Yin combined with deficient fire and stasis heat,and elderly individuals often present with deficiency of spleen and kidney combined with cold-dampness and stasis obstruction.By analyzing the common pathogenic mechanisms,outcome characteristics,and internal mechanisms among different age groups,this study provides a basic syndrome framework and core intervention strategies for specific populations in clinical practice,offering a new evidence-based approach to addressing the dilemma of"no identifiable syndrome".