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急性区域性隐匿性外层视网膜病变的研究进展OA

Advances in the Research of Acute Zonally Occult Outer Retinal Disease

中文摘要英文摘要

急性区域性隐匿性外层视网膜病变(AZOOR)是一种罕见且严重的外层视网膜疾病,通常表现为单眼或双眼受累,尤其多见于年轻女性及近视人群.这种疾病对患者的视力和生活质量造成了显著的影响.近年来,关于AZOOR的发病机制及其治疗的研究逐渐增多.本文根据现有研究总结了AZOOR的发病机制,主要由光感受器的特发性炎症引起,还可能与自身免疫反应、病毒感染及真菌感染等因素相关.在AZOOR的治疗现状方面,西医治疗方法包括糖皮质激素治疗、免疫抑制剂治疗、抗病毒治疗、抗真菌治疗、营养神经治疗、抗凝治疗以及光动力疗法等.近年来,中医药逐渐参与到AZOOR的临床治疗中,为该病的治疗提供了新的思路.目前,单纯的中医药治疗较为少见,多数情况下是与西医常规治疗联合应用,多采用中医综合治疗方案,包括中药、针灸、穴位注射、按摩、拔罐和刺络放血等疗法.本文通过对AZOOR的病因、危险因素及发病机制的归纳,重点总结了AZOOR治疗的具体方法及其临床疗效,旨在为临床诊治AZOOR提供有益的参考和思路.

Acute zonally occult outer retinal disease(AZOOR)is a rare and severe outer retinal disorder,commonly presenting with unilateral or bilateral involvement,particularly prevalent among young females and myopic individuals.This condition significantly impacts pa-tients'vision and quality of life.In recent years,research studies focusing on the pathogenesis and treatment of AZOOR have been increasing.According to existing studies,this paper summa-rizes the pathogenesis of AZOOR,primarily attributed to idiopathic inflammation of photorecep-tors,and may also relate to autoimmune responses,viral infections,and fungal infections.Re-garding the current treatment landscape for AZOOR,conventional Western Medicine ap-proaches include glucocorticoid therapy,immunosuppressive therapy,antiviral treatment,anti-fungal treatment,neuroprotective therapy,anticoagulation therapy,and photodynamic therapy.In recent years,Traditional Chinese Medicine(TCM)has gradually begun to play a role in the clinical management of AZOOR,offering new perspectives for treatment.Currently,single TCM treatment is relatively rare,with most cases involving a combination with conventional Western Medicine approaches.Integrated treatment strategies often include Chinese medicine,acupunc-ture,acupoint injection,massage,cupping,and blood-letting therapy.This paper summarizes the etiology,risk factors,and pathogenesis of AZOOR,with a particular focus on specific treat-ment methods and their clinical effi-cacy,aiming to provide valuable refer-ences and insights for the clinical diag-nosis and treatment of AZOOR.

齐冬晓;王超;廖炳光

成都中医药大学附属绵阳医院,绵阳 621000||连云港市中医院,连云港 222004成都中医药大学附属绵阳医院,绵阳 621000成都中医药大学附属绵阳医院,绵阳 621000||国家中医药管理局廖品正国医大师工作室传承中心,成都 610084

医药卫生

急性区域性隐匿性外层视网膜病变发病机制特发性炎症治疗

acute zonally occult outer retinal diseasepathogenesisidiopathic inflammationtreatment

《中国中医眼科杂志》 2026 (4)

390-394,400,6

四川中医药文化传承与研究中心课题(2018Y004)

10.13444/j.cnki.zgzyykzz.2026.04.017

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