浅谈mRNA疫苗的临床安全性及评价OA
A brief discussion on the clinical safety and evaluation of mRNA vaccines
信使核糖核酸(mRNA)疫苗为较新的疫苗技术路线,目前已应用于多传染病领域疫苗研发.为确保受试者安全,mRNA疫苗的安全性评价仍是目前疫苗临床研发中需关注的重点.本文结合目前已上市的预防性mRNA疫苗的临床安全性及评价,对预防性mRNA疫苗的安全性评价进行探讨.
Messenger ribonucleic acid(mRNA)vaccines represent a relatively new vaccine technology and have currently been applied to vaccine development across multiple infectious disease areas.To ensure the safety of participants,the safety evaluation of mRNA vaccines remains a key focus in current vaccine clinical research.This article discusses the safety assessment of preventive mRNA vaccines,drawing on clinical safety data and evaluations from currently marketed vaccines.
刘琳玉;鲁爽
国家药品监督管理局药品审评中心,北京,100076国家药品监督管理局药品审评中心,北京,100076
医药卫生
mRNA疫苗2019冠状病毒病mRNA疫苗呼吸道合胞病毒mRNA疫苗安全性安全性评价
mRNA vaccinescorona virus disease 2019 mRNA vaccinesrespiratory syncytial virus mRNA vaccinessafetysafety evaluation
《中国临床药理学杂志》 2026 (3)
434-438,5
药品监管科学全国重点实验室基金资助项目(2024SKLDRS0229)
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