湖北省随县一起人感染布鲁氏菌病畜间流行病学调查与处置OA

[Objectives]The cause and risk factors of a confirmed case of brucellosis infection among a livestock farmer at a recreational resort farm in Suixian County,Hubei Province in May 2025 were promptly in-vestigated to interrupt the transmission chain and control the risk of spread.[Methods]On-site investigations were conducted at the patient's farm,along with emergent screenings of cattle and sheep farmers within a radius of 10 km.Samples of serum from cattle and sheep were collected for detecting antibody against Brucella,and screening of Brucella was conducted among relevant personnel.Epidemiological analysis of animal popula-tions and measures of emergency treatment were implemented.[Results]No other abnormalities or reports of livestock abortion was found at other farms except for the site associated with this incident.19 sheep from the patient's farm were subjected to comprehensive sampling and testing of blood,and 2 were confirmed to be posi-tive for brucellosis.534 samples of serum from cattle and sheep were screened and monitored,with results of detecting antibody against Brucella being negative.The results for screening brucellosis were negative for all contacts and sampling personnel.The results of analyzing etiology showed that vehicles of transporting sheep from high-risk areas in other provinces entered the farming zone and purchased forage without proper cleaning and disinfection,and personnel came into contact with the aborted products of sheep without protective condi-tions,resulting in human infection.Positive sheep were culled and subjected to harmless disposal,with thor-ough cleaning and disinfection of the surrounding environment.The flock of infected sheep in the farm under-went another whole-flock testing 3 months later,and the results were all negative.[Conclusions]Comprehensive prevention and control measures for Brucellosis including controlling input risk,ensuring the intensity of moni-toring,building a strong biological safety barrier for farms,and conducting publicity and training for practitio-ners should be strengthened.