不同襻夹角对有效人工晶状体位置的影响研究OA
Effect of different haptic angles on the effective intraocular lens position
目的 利用 CASIA2 对比分析两种襻夹角人工晶状体(IOL)植入术后对有效 IOL位置(ELP)的影响.方法 本研究采用随机双盲前瞻性研究方法,选取 2024 年 6 月至2025 年6 月期间河北省眼科医院白内障科收治的年龄相关性白内障患者60 例(60 眼)为研究对象.依据植入的 IOL 不同将受试者随机分为两组:30 例(30 眼)接受0°襻夹角 IOL植入为0°襻夹角组,30 例(30 眼)植入 5°襻夹角 IOL 为 5°襻夹角组.对比两组患者术后1 d、1 周、1 个月、3 个月的裸眼视力(UCVA)、最佳矫正视力(BCVA)、ELP 及屈光度的变化,评估不同襻夹角对 IOL 位置的影响.结果 两组患者术后所有时间点的 UCVA、BCVA均较术前显著改善(均为 P<0.001),术后 1 d,0°襻夹角组患者 UCVA 优于 5°襻夹角组(P=0.041).各随访点的 ELP 比较,0°襻夹角组患者术后1 周的 ELP 较术后1d 前移,术后1 个月、3 个月较术后1 周后移(均为 P<0.05);5°襻夹角组患者术后 1 周、1 个月及 3个月的 ELP 均较术后1d 前移(均为 P<0.001).两组患者间 ELP 相比,术后1 d、1 周、1个月差异均有统计学意义(均为 P<0.05).0°襻夹角组患者术后3 个月 ELP 均方根低于5°襻夹角组(P=0.013).0°襻夹角组患者术后3 个月较术后1 d ELP 净位移量显著低于5°襻夹角组(P<0.001).0°襻夹角组患者屈光度术后1 周与术后1 d、1 个月、3 个月相比差异均有统计学意义(均为 P<0.05),表现为先远视漂移再近视漂移.5°襻夹角组患者屈光度术后1d 与术后1 周、1 个月及3 个月相比差异均有统计学意义(均为 P<0.001),表现为近视漂移.Spearman 相关性分析结果显示,术后屈光度变化与 ELP 变化呈显著正相关关系(rs=0.813,P<0.001).结论 0°和5°襻夹角的 IOL 均可有效改善患者视觉质量,术后1 个月在囊袋内均基本达到稳定状态.0°襻夹角 IOL 较 5°襻夹角 IOL 术后在囊袋内的轴向位移更小,屈光状态也更加稳定;5°襻夹角 IOL 术后仍存在远视漂移.
Objective To compare and analyze the effect of two kinds of haptic angle intraocular lens(IOL)implan-tation on the effective IOL position(ELP)using CASIA2.Methods A randomized double-blind prospective study was conducted,enrolling 60 patients(60 eyes)with age-related cataract admitted to the Department of Cataract,Hebei Eye Hos-pital from June 2024 to June 2025.According to the type of IOL implanted during the operation,the patients were divided in-to two groups:one group of 30 patients(30 eyes)received 0° haptic angle IOL implantation(0° haptic angle group),and the other group of 30 patients(30 eyes)received 5° haptic angle IOL implantation(5° haptic angle group).The changes in uncorrected visual acuity(UCVA),best-corrected visual acuity(BCVA),ELP,and diopter at 1 day,1 week,1 month,and 3 months after surgery were compared between the two groups of patients,and the effects of different haptic angles on IOL position were evaluated.Results The UCVA and BCVA of patients in the two groups significantly improved at all time points after operation compared with those before operation(all P<0.001).At 1 day after operation,the UCVA of patients in the 0° haptic angle group was better than that in the 5° haptic angle group(P=0.041).Compared with the mean ELP at each follow-up point,the ELP at 1 week after operation in the 0° haptic angle group was moved forward compared with that at 1 day after operation,and the ELP at 1 month and 3 months after operation was moved backward compared with that at 1 week after operation(all P<0.05).The ELP of patients in the 5° haptic angle group at 1 week,1 month,and 3 months af-ter operation was moved forward compared with that at 1 day after operation(all P<0.001).There were significant differ-ences in ELP between the two groups at 1 day,1 week,and 1 month after operation(all P<0.05).The ELP root mean square of patients in the 0° haptic angle group was lower than that in the 5° haptic angle group at 3 months after operation(P=0.013).The net displacement of ELP in the 0° haptic angle group was significantly lower than that in the 5° haptic an-gle group at 3 months after operation(P<0.001).There was a statistically significant difference in diopter at 1 week after operation compared with that at 1 day,1 month,and 3 months after operation in the 0° haptic angle group(all P<0.05),which showed hyperopia drift first and then myopia drift.There was a statistically significant difference in diopter at 1 day after operation compared with that at 1 week,1 month,and 3 months after operation in the 5° haptic angle group(all P<0.001),showing myopia drift.Spearman correlation analysis showed that there was a significant positive correlation be-tween the change in postoperative diopter and the change in ELP(rs=0.813,P<0.001).Conclusion Both0° haptic an-gle IOL and 5° haptic angle IOL can effectively improve the visual quality of patients.One month after surgery,it basically reaches a stable state in the capsular bag.The axial displacement of the 0°haptic angle IOL in the capsular bag is smaller than that of the 5°haptic angle IOL,and the refractive state of the former is more stable.There is still hyperopia drift after 5° haptic angle IOL implantation.
张鑫;张越;许衍辉;陈志敏
050017 河北省石家庄市,河北医科大学眼科学教研室||054001 河北省邢台市,河北省眼科医院白内障科,河北省眼科学重点实验室,河北省眼部疾病临床医学研究中心054001 河北省邢台市,河北省眼科医院白内障科,河北省眼科学重点实验室,河北省眼部疾病临床医学研究中心054001 河北省邢台市,河北省眼科医院白内障科,河北省眼科学重点实验室,河北省眼部疾病临床医学研究中心054001 河北省邢台市,河北省眼科医院白内障科,河北省眼科学重点实验室,河北省眼部疾病临床医学研究中心
医药卫生
白内障人工晶状体有效人工晶状体位置轴向位置襻夹角
cataractintraocular lenseffective intraocular lens positionaxial positionhaptic angle
《眼科新进展》 2026 (4)
296-301,6
中央引导地方科技发展资金项目(编号:246Z7710G)
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