首页|期刊导航|生物骨科材料与临床研究|两种不同的脊柱微创融合手术方式治疗腰椎退行性疾病的疗效比较研究

两种不同的脊柱微创融合手术方式治疗腰椎退行性疾病的疗效比较研究OA

A comparative study on the efficacy of two minimally invasive spinal fusion techniques for lumbar degenerative diseases

中文摘要英文摘要

目的 对比单侧双入路内窥镜腰椎椎间融合术(unilateral biportal endoscopic transforaminal lumbar interbody fusion,ULIF)和全脊柱内镜下经椎板间隙入路椎间融合内固定术(full-endoscopic posterior lumbar interbody fusion,Endo-PLIF)的治疗腰椎退行性疾病(lumbar degenerative diseases,LDD)的临床疗效.方法 回顾性分析2021年1月至2024年1月期间青海红十字医院收治的120例腰椎退行性疾病患者.根据严格的纳入与排除标准,患者被分为ULIF组(63例,采用ULIF)和Endo-PLIF组(57例,采用Endo-PLIF).回顾性分析了两组患者的术中切口长度、术中失血量、术前及术后椎间盘和椎间孔高度、背部与腿部VAS评分、ODI评分、并发症发生率、满意度(改良MacNab评分)及融合率(Bridwell分级).结果 纳入本研究的120例患者均完成术后12个月的随访.结果 显示,Endo-PLIF组的手术时间显著长于ULIF组,切口长度显著小于ULIF组(P<0.05);但两组术后住院时间差异无统计学意义(P>0.05).术后3 d的椎间盘高度和椎间孔高度ULIF组显著高于Endo-PLIF组(P<0.001).两组患者的VAS评分和ODI评分较术前均有所改善,ULIF组在术后3 d的腰痛VAS评分、术后3 d及3个月的腿痛VAS评分和ODI评分均优于Endo-PLIF组(P<0.05).末次随访时,ULIF组满意度为96.8%,Endo-PLIF组为94.7%;融合率分别为95.2%和93%,差异无统计学意义(P>0.05).两组并发症发生率均较低,且差异无统计学意义(P>0.05).结论 ULIF术式在术后早期疼痛缓解、功能恢复、椎间隙及椎间孔高度改善方面表现出显著优势,而Endo-PLIF在术中创伤控制方面更具优势.两种术式在12个月随访时均可实现较高的患者满意度和稳定的融合率,显示出疗效相当的特性.

Objective To compare the clinical efficacy of unilateral biportal endoscopic transforaminal lumbar interbody fusion(ULIF)and full-endoscopic posterior lumbar interbody fusion(Endo-PLIF)in treating lumbar degenerative diseases(LDD).Methods A retrospective analysis was performed on 120 patients with lumbar degenerative diseases(LDD)who received surgical treatment between January 2021 and January 2024.Patients were allocated to either the ULIF group(n=63)or the Endo-PLIF group(n=57)according to strict inclusion and exclusion criteria.Patients in the ULIF group underwent unilateral biportal endoscopic lumbar interbody fusion,while those in the Endo-PLIF group received full-endoscopic interlaminar lumbar interbody fusion with internal fixation.Intraoperative data,including incision length and estimated blood loss were recorded.Disc and foraminal heights were assessed via radiographic measurements preoperatively and at multiple postoperative time points.Clinical outcomes included VAS scores for back and leg pain,ODI scores,complication rates,patient satisfaction(evaluated by the modified MacNab criteria),and fusion status(graded using the Bridwell classification).All 120 patients successfully completed the 12-month postoperative follow-up.Results The Endo-PLIF group demonstrated significantly longer operative times and smaller incision lengths compared to the ULIF group(P<0.05).No significant difference in postoperative hospital stay was observed between the two groups(P>0.05).Three days after surgery,disc and foraminal heights were significantly greater in the ULIF group than in the Endo-PLIF group(P<0.001).Significant improvements in both VAS and ODI scores were observed in both groups compared to baseline values.The ULIF group showed greater reductions in low back pain VAS scores on postoperative day 3,as well as in leg pain VAS and ODI scores at day 3 and at 3 months after surgery(P<0.05).At the final follow-up,patient satisfaction remained high in both groups,with 96.8%in the ULIF group and 94.7%in the Endo-PLIF group.Fusion rates were 95.2%in the ULIF group and 93.0%in the Endo-PLIF group,with no statistically significant difference(P>0.05).Both procedures had low complication rates,and adverse events did not significantly differ between groups.Conclusion ULIF demonstrated advantages in early pain relief and functional recovery,along with more substantial restoration of disc and foraminal height.Conversely,Endo-PLIF was associated with reduced intraoperative soft tissue trauma.By the 12-month follow-up,both procedures achieved comparable fusion rates and patient satisfaction,supporting their equivalent efficacy.

王彧;李占银;郝岩;朱超

青海红十字医院脊柱外科,青海 西宁,810000青海红十字医院脊柱外科,青海 西宁,810000青海红十字医院脊柱外科,青海 西宁,810000南京医科大学附属江宁医院骨科,江苏 南京,211100

医药卫生

单侧双入路内窥镜腰椎椎间融合术全脊柱内镜下经椎板间隙入路椎间融合内固定术腰椎退行性疾病

Unilateral biportal endoscopic transforaminal lumbar interbody fusionFull-endoscopic posterior lumbar interbody fusionLumbar degenerative disease

《生物骨科材料与临床研究》 2026 (2)

26-33,8

10.3969/j.issn.1672-5972.2026.02.005

评论