基于神经核团谐振的经皮电刺激睡眠调控方法与效果评估OA

To examine the sleep-modulatory effects of transcutaneous electrical nerve stimulation(TENS)based on neural nuclei resonance,30 healthy participants were assigned to either a sham stimulation group or a TENS(123~127 Hz)group,each group was intervened 30 min.Sleep electroencephalogram(EEG)was recorded for 60 min and evaluated using both objective and subjective measures.The results showed that among participants with poor sleep quality,the TENS group exhibited bidirectional emotional im-provements,with increased positive emotions(P＝0.048)and decreased negative emotions(P＝0.002).TENS decreased the gravity frequency of EEG(P＝ 0.009),and reduced neuronal discharge frequency with stable dominance of δ and θ activity during sleep.Mo-reover,sleep efficiency increased,the proportion of N3 sleep was enhanced,the stability of N2 and N3 stages improved,and abnormal arousals were reduced.The research demonstrate that TENS with specific frequency waveforms effectively promotes low-frequency EEG activity,optimizes sleep architecture and improves emotional state,offering a novel non-pharmacological intervention for insomnia.