Advancing cancer research:Cutting-edge insights from colorectal cancer patient-derived xenograft mouse modelsOA
Advancing cancer research:Cutting-edge insights from colorectal cancer patient-derived xenograft mouse models
Yalan Lu;Xiaokang Lei;Yanfeng Xu;Yanhong Li;Ruolin Wang;Siyuan Wang;Aiwen Wu;Chuan Qin
NHC Key Laboratory of Human Disease Comparative Medicine,Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases,International Center for Technology and Innovation of Animal Model,Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)& Comparative Medicine Center,Peking Union Medical College(PUMC),Beijing 100021,ChinaKey Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Name of Department of Unit Ⅲ & Ostomy Service,Gastrointestinal Cancer Center,Peking University Cancer Hospital & Institute,Beijing 100142,ChinaNHC Key Laboratory of Human Disease Comparative Medicine,Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases,International Center for Technology and Innovation of Animal Model,Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)& Comparative Medicine Center,Peking Union Medical College(PUMC),Beijing 100021,ChinaNHC Key Laboratory of Human Disease Comparative Medicine,Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases,International Center for Technology and Innovation of Animal Model,Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)& Comparative Medicine Center,Peking Union Medical College(PUMC),Beijing 100021,ChinaNHC Key Laboratory of Human Disease Comparative Medicine,Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases,International Center for Technology and Innovation of Animal Model,Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)& Comparative Medicine Center,Peking Union Medical College(PUMC),Beijing 100021,ChinaNHC Key Laboratory of Human Disease Comparative Medicine,Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases,International Center for Technology and Innovation of Animal Model,Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)& Comparative Medicine Center,Peking Union Medical College(PUMC),Beijing 100021,ChinaState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers,Beijing Key Laboratory of Carcinogenesis and Translational Research,Department of Unit Ⅲ & Ostomy Service,Gastrointestinal Cancer Center,Peking University Cancer Hospital & Institute,Beijing 100142,ChinaNHC Key Laboratory of Human Disease Comparative Medicine,Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases,International Center for Technology and Innovation of Animal Model,Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS)& Comparative Medicine Center,Peking Union Medical College(PUMC),Beijing 100021,China||Changping National Laboratory(CPNL),Beijing 102200,China
Colorectal cancerDrug screeningPatient-derived xenograftmodelPrecision medicinePreclinical trialResistanceTranslational researchTumor evolution
Colorectal cancerDrug screeningPatient-derived xenograftmodelPrecision medicinePreclinical trialResistanceTranslational researchTumor evolution
《基因与疾病（英文）》 2026 (1)
323-334,12
This work was supported by the National Natural Science Foundation of China(No.82303782),Beijing Natural Sci-ence Foundation(No.7252096),the Young Elite Scientists Sponsorship Program by CAST(No.2022QNRC001),and the Non-Profit Central Research Institute Fund of the Chinese Academy of Medical Sciences(No.2023-PT180-01).
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