规模猪场批次化生产精准免疫对猪流行性腹泻的防控效果研究OA

To explore the prevention and control effect of precise immunization on porcine epidemic diarrhea(PED)in batch production,a PED-affected pig herd in a pig farm in north China treated with intervention involving vaccinating all the sows with an inactivated PED vaccine,followed by a booster immunization 21 days later.Concurrently,discontinuing the foster care of piglets in the farrowing house,weaning severe cases early,cutting off feed,providing rehydration and oral gentamicin.Sows in the farrowing house were fed Altrenogesterone to ensure stable batch production.After the farrowing house was emptied,it underwent thorough cleaning and disinfection,followed by high-temperature drying at 60 ℃ for 3 h.The results showed that after the implementation of the plan,the disease situation of the pig herd improved significantly.The diarrhea rate of breeding sows,the piglets and the mortality rate were all extremely significantly lower than those of the batch before the implementation of the plan(P＜0.01),respectively,and at the same time,the average weight of weaned piglets was extremely significantly higher than that of the batch before the implementation(P＜0.01).Two months later,the positive rate of PED virus antibody in sows was 100%,the average S/P was about 5.00,and the pathogen detection of PED in the pig herd turned negative.The findings suggest that the precise immunization regimen of"first immunization+21-day booster immunization"in batch production effectively prevent and control the PED epidemic.