首页|期刊导航|中国实用神经疾病杂志|膈肌电刺激对重症脑卒中机械通气患者撤机成功率的影响

膈肌电刺激对重症脑卒中机械通气患者撤机成功率的影响OA

Effect of diaphragmatic electrical stimulation on weaning success rate in patients with severe stroke by mechanical ventilation

中文摘要英文摘要

目的 分析膈肌电刺激对重症脑卒中机械通气患者撤机成功率和并发症的影响.方法 收集2022-10-2024-10就诊于上海长征医院的100例重症脑卒中机械通气患者进行回顾性研究,将采用常规治疗的患者纳入对照组(47例),在对照组基础上联合膈肌电刺激治疗的患者纳入研究组(53例).比较2组预后情况(机械通气时间、住ICU时间、撤机成功率及48 h内重新上机情况)、膈肌功能、呼吸效率(浅快呼吸指数、最大呼气压、最大吸气压)、氧合指数、动脉氧分压及并发症情况.结果 对照组机械通气时间、住ICU时间分别为(7.23±1.22)d、(13.24±2.43)d,研究组分别为(6.62±1.15)d、(12.21±1.93)d,均显著低于对照组(P<0.05).研究组撤机成功率84.91%,显著高于对照组的65.96%.研究组48 h内重新上机率5.66%,显著低于对照组的19.15%(P<0.05).治疗第3天时,2组膈肌厚度变异率无统计学差异(P>0.05);治疗第7、14天时,2组膈肌厚度变异率均显著升高,研究组均显著高于对照组(P<0.05).研究组浅快呼吸指数显著低于对照组,最大呼气压、最大吸气压显著高于对照组(P<0.05).治疗第3天时,2组氧合指数、动脉氧分压均无统计学差异(P>0.05);治疗第7、14天时,2组氧合指数、动脉氧分压均显著上升,研究组显著大于对照组(P<0.05).对照组并发症发生率23.41%,研究组为15.09%,差异无统计学意义(P>0.05).结论 膈肌电刺激能有效改善重症脑卒中机械通气患者的膈肌功能,提升呼吸效率,从而提高撤机成功率,减少并发症,具有较高安全性.

Objective To analyze the effect of diaphragmatic electrical stimulation(DES)on weaning success rate and complications among critically ill stroke patients undergoing mechanical ventilation.Methods A retrospective study was conducted on 100 critically ill stroke patients undergoing mechanical ventilation admitted to Shanghai Changzheng Hospital from October 2022 to October 2024.Patients receiving conventional treatment were included in the control group(47 patients),and those receiving DES in addition to conventional treatment were included in the study group(53 patients).Outcomes were compared between the two groups,including prognosis indicators(duration of mechanical ventilation,length of ICU stay,weaning success rate,and reintubation within 48 hours),diaphragmatic function,respiratory efficiency,oxygenation index,arterial oxygen partial pressure,and complications.Results The duration of mechanical ventilation and length of ICU stay in the control group were(7.23±1.22)days and(13.24±2.43)days,respectively,while those in the study group were(6.62±1.15)days and(12.21±1.93)days,respectively,which were significantly shorter than those in the control group(P<0.05).The weaning success rate in the study group was 84.91%,which was significantly higher than 65.96%in the control group.The reintubation rate within 48 hours in the study group was 5.66%,which was significantly lower than 19.15%in the control group(P<0.05).No significant difference was observed in diaphragmatic thickness variability between the two groups on the third day of treatment(P>0.05).On the seventh day and fourteenth day of treatment,diaphragmatic thickness variability increased significantly in both groups,the study group had higher values than the control group(P<0.05).The rapid shallow breathing index in the study group was significantly lower,while the maximum expiratory pressure and maximum inspiratory pressure were significantly higher compared to the control group(P<0.05).On the third day of treatment,there were no significant differences in oxygenation index and arterial oxygen partial pressure between the two groups(P>0.05).However,on the seventh day and fourteenth day of treatment,both parameters increased significantly in both groups,the study group had higher values than the control group(P<0.05).The complication rate in the control group was 23.41%,which was 15.09%in the study group,with no significant difference(P>0.05).Conclusion DES can effectively improve diaphragmatic function and respiratory efficiency among critically ill stroke patients undergoing mechanical ventilation,thereby enhancing weaning success rate and reducing complications,demonstrating highly secure.

蒋艳秋;蔡爱旎;洪涵涵

海军军医大学第二附属医院,上海 200000海军军医大学第二附属医院,上海 200000海军军医大学第二附属医院,上海 200000

医药卫生

重症脑卒中膈肌电刺激机械通气撤机膈肌功能呼吸效率

Severe strokeDiaphragmatic electrical stimulationMechanical ventilationWithdrawal of mechanical ventilationDiaphragm functionRespiratory efficiency

《中国实用神经疾病杂志》 2026 (3)

363-367,5

上海市医院协会课题(编号:X2023043)

10.12083/SYSJ.250560

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