六字诀呼吸操对老年慢性阻塞性肺疾病稳定期患者的疗效评估OA
Evaluation of Efficacy of Liuzijue Breathing Exercises in Elderly Patients with Stable Chronic Obstructive Pulmonary Disease
目的 探讨六字诀呼吸操对老年慢性阻塞性肺疾病(COPD)稳定期患者的疗效.方法 采用随机对照临床研究方法,将老年COPD稳定期患者随机分成六字诀呼吸操治疗组、呼吸功能锻炼组及对照组.六字诀呼吸操每次30 min,1次/d;呼吸功能锻炼包括缩唇呼吸及腹式呼吸锻炼,每项15 min,共30 min,1次/d;对照组仅用常规药物治疗.比较3组患者治疗前、治疗24周的肺功能指标,改良版英国医学研究会呼吸问卷(mMRC)及COPD患者自我评估测试(CAT)评分,临床COPD问卷(CCQ),体重指数、气流受限、呼吸困难及运动能力(BODE)指数,血气指标,24周内急性加重次数及无急性加重生存时间(周).结果 六字诀治疗组患者治疗后的第1秒用力呼气容积(FEV1)、FEV1/用力肺活量%,FEV1/正常预计值%、mMRC、CAT、CCQ评分,BODE指数与呼吸功能锻炼组及对照组比较差异均有显著性(P<0.05),3组患者治疗前后呼气峰流速、动脉血氧分压及二氧化碳分压均未见显著性差异(P>0.05).随访24周发现六字诀治疗组急性加重次数显著低于呼吸功能锻炼组及对照组(P<0.01),六字诀治疗组无急性加重生存时间显著优于呼吸功能锻炼组及对照组(P<0.01).结论 六字诀呼吸操可以显著改善老年COPD稳定期患者的肺功能气流受限指标及症状评分,提高生活质量,减少急性加重次数及风险.
Objective To investigate the efficacy of Liuzijue breathing exercises in elderly patients with stable chronic obstructive pulmo-nary disease(COPD).Methods Randomized controlled trial was conducted to randomly divide elderly patients with stable COPD into Liuzijue treatment group,respiratory function exercise and control group.TCM Liuzijue breathing exercise for 30 minutes each time,once a day.Respiratory function exercises include pursed lip breathing exercises and abdominal breathing exercises,each 15 minutes,a total of 30 minutes,once a day,and the control group was treated with conventional drugs only.The pulmonary function indexes of the three groups before treatment and 24 weeks after treatment were recorded,Modified Medical British Research Council(mMRC)respiratory questionnaire and COPD assessment test(CAT),clinical COPD questionnaire(CCQ),body mass index,airflow obstruction,dyspnea,and exercise capacity index(BODE),partial pressure of arterial oxygen(PaO2),and arterial partial pressure of carbon dioxide(PaCO2),the number of exacerbations within 24 weeks and the time to survive without exacerbations(weeks),Whether there was any statistical dif-ference between the three groups of the above indicators was compared.Results There were significant differences in FEV1,FEV1/FVC%,FEV1/pre%,mMRC,CAT,CCQ,BODE between the Liuziji treatment group and the respiratory exercise group and the control group after treatment(P<0.05),and there were no significant differences in PEF,PaO2 and PaCO2 between the three groups before and af-ter treatment(P>0.05).After 24 weeks of follow-up,it was found that the number of acute exacerbations in the Liuzijue treatment group was significantly lower than that in the respiratory function exercise group and the control group(P<0.01),and the survival time(weeks)withoutacute exacerbation in the Liuzijue treatment group was significantly better than that in the respiratory exercise group and the con-trol group(P<0.01).Conclusion Liuzijue breathing exercises can significantly improve the pulmonary function airflow limitation index and symptom score,improve the quality of life,and reduce the number of acute exacerbations in elderly patients with stable COPD.
徐晓光;朱晓旭;孙桂莉;杜敏娟;王蔚;王靓雅
吉林医药学院附属医院 呼吸与危重症医学科,吉林 吉林 132013吉林医药学院附属医院 呼吸与危重症医学科,吉林 吉林 132013吉林医药学院附属医院 呼吸与危重症医学科,吉林 吉林 132013吉林医药学院附属医院 呼吸与危重症医学科,吉林 吉林 132013吉林医药学院附属医院 呼吸与危重症医学科,吉林 吉林 132013吉林医药学院附属医院 呼吸与危重症医学科,吉林 吉林 132013
医药卫生
六字诀呼吸操慢性阻塞性肺疾病稳定期疗效
liuzijue breathing exerciseschronic obstructive pulmonary diseasestable stageefficacy
《吉林医药学院学报》 2026 (2)
113-118,123,7
吉林省中医药科技项目(2024318)
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