Identification of immune reconstitution and hematopoiesis restoration by scRNA-seq in bone marrow of multiple myeloma patients treated with high-dose melphalan following auto-HSCTOA
Identification of immune reconstitution and hematopoiesis restoration by scRNA-seq in bone marrow of multiple myeloma patients treated with high-dose melphalan following auto-HSCT
Qian Li;Jing Ma;Su Liu;Zeng Cao;Haifeng Zhao;Yufei Wang;Shihui Li;Pan Lv;Huihui Zhang;Guowen Wang;Guang Yang;Yaling Wang;Xiaodong Zhang;Yafei Wang;Hongfeng Yuan;Qiaomei Cai;Lina Zhao;Li Lin;Shuang Gao;Lin Chen;Zhiying Zhang
Department of Hematology,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center of Cancer,Tianjin Key Laboratory of Cancer Prevention and Therapy,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,China||Department of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,ChinaDepartment of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,ChinaDepartment of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,ChinaDepartment of Hematology,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center of Cancer,Tianjin Key Laboratory of Cancer Prevention and Therapy,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaDepartment of Hematology,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center of Cancer,Tianjin Key Laboratory of Cancer Prevention and Therapy,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaState Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaState Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaState Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaState Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaNational Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin's Clinical Research Center for Cancer,Department of Bone and Soft Tissue Tumors,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin 300060,ChinaState Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaState Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaState Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaDepartment of Hematology,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center of Cancer,Tianjin Key Laboratory of Cancer Prevention and Therapy,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,China||Department of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,ChinaState Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaState Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaDepartment of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,China||State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,ChinaDepartment of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,ChinaDepartment of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,ChinaDepartment of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,ChinaDepartment of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,China
《癌症生物学与医学（英文版）》 2026 (2)
247-251,5
This work was supported by the National Natural Science Foundation of China(Grant Nos.82270208 to Ya-fei Wang and 82372818 to Xiao-dong Zhang)and was supported by the"Clinical-Basic"Co-Pl Program(Grant No.20250206)of Tianjin Medical University Cancer Institute&Hospital.This work was funded by Tianjin Key Medical Discipline Construction Project(Grant No.TJYXZDXK-3-003A).
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