Pan-KRAS inhibition:unlocking broad-spectrum targeted therapy for KRAS-mutant cancersOA

作者：Juanjuan Feng;Xuanzheng Xiao;Zhengke Lian;Ao Zhang;Xiufeng Pang

作者单位：Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences,East China Normal University,Shanghai 200241,China||Department of Pathogenic Microbiology and Immunology,School of Basic Medical Sciences,Xi'an Jiaotong University,Xi'an 710061,ChinaShanghai Frontiers Science Center for Drug Target Identification and Delivery,State Key Laboratory of Innovative Immunotherapy,School of Pharmaceutical Sciences,Shanghai Jiao Tong University,Shanghai 200240,ChinaShanghai Key Laboratory of Regulatory Biology and School of Life Sciences,East China Normal University,Shanghai 200241,ChinaShanghai Frontiers Science Center for Drug Target Identification and Delivery,State Key Laboratory of Innovative Immunotherapy,School of Pharmaceutical Sciences,Shanghai Jiao Tong University,Shanghai 200240,ChinaShanghai Key Laboratory of Regulatory Biology and School of Life Sciences,East China Normal University,Shanghai 200241,China||Chongqing Institute of East China Normal University,Chongqing 401120,China

刊名：《癌症生物学与医学（英文版）》 2026 (2)

页码/页数：162-168,7

基金：This work was supported by the National Natural Science Foundation of China(Grant Nos.82472677,82404653,U25A20103,and 223B2704),the Natural Science Foundation of Shanghai(Grant No.23ZR1418900),and the Natural Science Foundation of Chongqing(Grant No.CSTB2023NSCQ-MSX0367).

DOI：10.20892/j.issn.2095-3941.2025.0612