肺结节患者胸腔镜术后并发症风险的预测模型分析OA
A prediction model for complication risk following thoracoscopic surgery in patients with pulmonary nodules
目的 探讨肺结节患者胸腔镜术后并发症风险的关键因素及其预测模型的价值.方法 选取中国人民解放军联勤保障部队第九八九医院在2022年1月至2025年3月106例胸腔镜肺结节切除术患者,根据术后30 d内是否发生并发症,分为并发症组(n=22)、无并发症组(n=84).收集患者基线资料,分析胸腔镜肺结节切除术后并发症的危险因素,并构建预测模型.结果 并发症组年龄>45岁、合并慢性阻塞性肺疾病(COPD)、术中出血量≥200 mL、手术时间≥120 min患者占比高于无并发症组(P<0.05);经多因素Logistic回归分析,年龄>45岁、合并COPD、术中出血量≥200 mL、手术时间≥120 min是影响肺结节患者胸腔镜术后并发症的独立危险因素(P<0.05);将危险因素作为预测因子构建预测模型,受试者操作特征(ROC)曲线表明:曲线下面积(AUC)为0.814,标准误为0.072,95%CI为0.759~0.917,灵敏度为0.821,特异度为0.874.结论 年龄、合并COPD、术中出血量、手术时间均是影响肺结节患者胸腔镜术后并发症的独立危险因素,且以上变量构建的预测模型具备较高的预测效能.
[Objective]To develop a prediction model for complication risk in patients with pulmonary nodules undergoing thoracoscopic surgery and investigate its predictive value.[Methods]A total of 106 patients who underwent thoracoscopic pulmonary nodule resection at the 989th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army from January 2022 to March 2025 were included.Based on the occurrence of complications within 30 days postoperatively,they were divided into a complication group(22 cases)and a non-complication group(84 cases).Baseline data were collected,and multivariate logistic regression analysis was performed to identify key factors influencing postoperative complications.A prediction model was subsequently constructed.[Results]The proportion of patients aged over 45 years with chronic obstructive pulmonary disease(COPD),intraoperative bleeding≥200 mL and operation time≥120 min in the complication group was higher than that in the non-complication group(P<0.05).Multivariate logistic regression analysis showed that the age of over 45 years old,COPD,intraoperative blood loss≥200 mL and operation time≥120 min were independent risk factors for complications after thoracoscopic surgery in patients with pulmonary nodules(P<0.05).A prediction model incorporating the above risk factors demonstrated an area under the receiver operating characteristic curve(AUC)of 0.814(standard error:0.072;95%CI:0.759-0.917),with sensitivity and specificity of 0.821 and 0.874,respectively.[Conclusion]Age,COPD,intraoperative blood loss and operation time are all independent risk factors for complications after thoracoscopic surgery in patients with pulmonary nodules,and the prediction model based on the above variables has good predictive value.
王凯;崔文博;杨战航
中国人民解放军联勤保障部队第九八九医院 心胸外科,河南 平顶山 467000中国人民解放军联勤保障部队第九八九医院 心胸外科,河南 平顶山 467000中国人民解放军联勤保障部队第九八九医院 皮肤科,河南 平顶山 467000
医药卫生
肺结节胸腔镜并发症预测模型术中出血量
pulmonary nodulesthoracoscopypostoperative complicationsprediction modelintraoperative blood loss
《中国医学工程》 2026 (2)
50-54,5
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