单细胞测序在畜禽上的应用OA

Traditional population-level sequencing struggles to resolve cellular heterogeneity,hindering precise research and breeding in the livestock and poultry sector.Single-cell sequencing has developed into genomic,transcriptomic,and epigenomic sequencing technologies.This paper systematically outlines its core principles and processes,focusing on its applications in livestock and poultry reproduction,development,immunology,nutritional metabolism,etc.,and analyzes its practices in the genetic breeding of cattle,pigs,poultry,etc.Its core value lies in breaking the population average effect,accurately capturing cellular heterogeneity and developmental dynamics,deciphering the molecular mechanisms of economic traits such as meat quality and lactation,and screening key genetic markers.Currently,it has achieved remarkable results in optimizing cattle lactation,improving pork quality,enhancing poultry egg-laying performance,and disease prevention and control.