经皮穴位电刺激疗法对固定平台单髁置换术后早期疼痛影响的临床研究OA
A clinical study of the effect of transcutaneous electric acupoint stimulation on early pain after fixed-bearing unicompartmental knee arthroplasty
目的:观察经皮穴位电刺激疗法(transcutaneous electric acupoint stimulation,TEAS)对固定平台单髁置换术(fixed-bearing unicompartmental knee arthroplasty,FB-UKA)后早期疼痛的影响.方法:将2023年5月至2024年5月收治的60例膝关节内侧间室骨关节炎患者随机分为2组,每组30例.均采用FB-UKA治疗.术后7 d内,常规镇痛组采用常规多模式镇痛,穴位电刺激组在常规多模式镇痛方案基础上联合TEAS镇痛,必要时2组患者均额外使用盐酸曲马多镇痛.分别于术前及术后12 h、1 d、3 d、5 d、7 d评定患者的膝关节静息和运动疼痛视觉模拟量表(visual analogue scale,VAS)评分、美国特种外科医院(Hospital for Special Sur-gery,HSS)膝关节评分;术后4周,评定患者的关节遗忘评分(forgotten joint score,FJS);同时记录患者术后首次使用盐酸曲马多的时间、术后7 d内盐酸曲马多使用量,以及患者发生胃肠道反应的情况.结果:①一般情况.穴位电刺激组1例患者术后首次治疗时出现穴位电刺激敷贴过敏,主动退出试验;常规镇痛组1例患者术后出现下肢深静脉血栓,退出试验;最终每组各纳入29例.②膝关节静息疼痛VAS评分.时间因素与分组因素之间不存在交互效应(F=0.518,P=0.762).膝关节静息疼痛VAS评分随时间变化呈先升高后降低的趋势,存在时间效应(F=81.321,P=0.000).穴位电刺激组膝关节静息疼痛VAS评分低于常规镇痛组(F=24.335,P=0.000).③膝关节运动疼痛VAS评分.时间因素与分组因素之间不存在交互效应(F=1.000,P=0.427).膝关节运动疼痛VAS评分随时间变化呈先升高后降低的趋势,存在时间效应(F=63.941,P=0.000).穴位电刺激组膝关节运动疼痛VAS评分低于常规镇痛组(F=16.688,P=0.000).④HSS膝关节评分.2组HSS膝关节评分随时间变化均呈先降低后升高的趋势(F=1 690.819,P=0.000;F=1 578.109,P=0.000).除术前外(t=1.263,P=0.212),术后 12 h、1 d、3 d、5 d、7 d 穴位电刺激组的 HSS 膝关节评分均高于常规镇痛组(t=2.829,P=0.006;t=7.130,P=0.000;t=5.866,P=0.000;t=3.943,P=0.000;t=3.753,P=0.000).⑤FJS.术后4周,穴位电刺激组的FJS高于常规镇痛组(t=5.609,P=0.000).⑥术后镇痛药额外使用情况.所有患者术后均额外使用了盐酸曲马多镇痛,穴位电刺激组的术后首次使用时间晚于常规镇痛组(t=5.055,P=0.000),术后7 d内盐酸曲马多使用量少于常规镇痛组(t=-3.477,P=0.001).⑦胃肠道反应发生率.试验期间,穴位电刺激组2例患者出现恶心、呕吐等胃肠道反应,常规镇痛组8例出现胃肠道反应,行止吐、护胃治疗后均缓解.穴位电刺激组胃肠道反应发生率低于常规镇痛组(x2=4.350,P=0.037).结论:在常规多模式镇痛的基础上应用TEAS,可有效减轻FB-UKA术后早期疼痛症状,减少镇痛药物的使用及由此导致的胃肠道反应,有助于膝关节功能恢复,效果优于单纯常规多模式镇痛.
Objective:To observe the effect of transcutaneous electric acupoint stimulation(TEAS)on early pain after fixed-bearing unicompartmental knee arthroplasty(FB-UKA).Methods:From May 2023 to May 2024,60 patients with medial compartment knee osteoar-thritis were randomly divided into 2 groups,with 30 cases in each group.All patients were treated with FB-UKA.Within 7 days after surgery,the routine analgesia group received routine multimodal analgesia,while the acupoint electric stimulation group received TEAS analgesia in addition to the routine multimodal analgesia regimen.Both groups were given additional tramadol hydrochloride for analgesia when necessary.Visual analogue scale(VAS)scores of knee joint rest and motion pain and Hospital for Special Surgery(HSS)knee scores were evaluated before surgery and at 12 hours and 1,3,5 and 7 days after surgery;at 4 weeks after surgery,the forgotten joint score(FJS)was evaluated.Meanwhile,the time of first use of tramadol hydrochloride after surgery,the total consumption of tramadol hydrochloride within 7 days after surgery,and the occurrence of gastrointestinal reactions were recorded.Results:①General information.One patient in the acu-point electric stimulation group developed allergy to acupoint electric stimulation patch during the first postoperative treatment and withdrew from the trial;one patient in the routine analgesia group developed deep vein thrombosis of the lower limb after surgery and withdrew from the trial;finally,29 cases were included in each group.②VAS score of knee joint rest pain.There was no interaction effect between time factor and grouping factor(F=0.518,P=0.762).The VAS score of knee joint rest pain showed a trend of increasing first and then decrea-sing with time,and there was a time effect(F=81.321,P=0.000).The VAS score of knee joint rest pain in the acupoint electric stimula-tion group was lower than that in the routine analgesia group(F=24.335,P=0.000).③VAS score of knee joint motion pain.There was no interaction effect between time factor and grouping factor(F=1.000,P=0.427).The VAS score of knee joint motion pain showed a trend of increasing first and then decreasing with time,and there was a time effect(F=63.941,P=0.000).The VAS score of knee joint motion pain in the acupoint electric stimulation group was lower than that in the routine analgesia group(F=16.688,P=0.000).④HSS knee score.The HSS knee scores of both groups showed a trend of decreasing first and then increasing with time(F=1 690.819,P=0.000;F=1 578.109,P=0.000).Except for pre-surgery(t=1.263,P=0.212),the HSS knee scores of the acupoint electric stimulation group at 12 hours and 1,3,5,and 7 days after surgery were higher than those of the routine analgesia group(t=2.829,P=0.006;t=7.130,P=0.000;t=5.866,P=0.000;t=3.943,P=0.000;t=3.753,P=0.000).⑤FJS.At 4 weeks after surgery,the FJS of the acupoint electric stimulation group was higher than that of the routine analgesia group(t=5.609,P=0.000).⑥Additional use of postoperative analgesics.All patients additionally used tramadol hydrochloride for analgesia after surgery.The time of first use after surgery in the acupoint electric stimulation group was later than that in the routine analgesia group(t=5.055,P=0.000),and the consumption of tramadol hydrochloride within 7 days after surgery was less than that in the routine analgesia group(t=-3.477,P=0.001).⑦Incidence of gastrointestinal reac-tions.During the trial,2 patients in the acupoint electric stimulation group developed gastrointestinal reactions such as nausea and vomiting,and 8 patients in the routine analgesia group developed gastrointestinal reactions,all of which were relieved after antiemetic and stomach-protecting treatments.The incidence of gastrointestinal reactions in the acupoint electric stimulation group was lower than that in the routine analgesia group(x2=4.350,P=0.037).Conclusion:The application of TEAS on the basis of routine multimodal analgesia can effectively relieve early pain after FB-UKA,reduce the use of analgesic drugs and the resulting gastrointestinal reactions,contribute to the recovery of knee joint function,and its effect is better than that of routine multimodal analgesia alone.
赵锦伟;周鑫;鞠昌军;高广凌;姜红江;黄明利
山东省文登整骨医院,山东 威海 264400山东省文登整骨医院,山东 威海 264400山东省文登整骨医院,山东 威海 264400山东省文登整骨医院,山东 威海 264400山东省文登整骨医院,山东 威海 264400山东省文登整骨医院,山东 威海 264400
关节成形术,置换,膝骨关节炎,膝疼痛,手术后固定平台单髁置换术经皮穴位电刺激随机对照试验专题
arthroplasty,replacement,kneeosteoarthritis,kneepain,postoperativefixed-bearing unicompartmental knee arthroplastytranscutaneous electric acupoint stimulationrandomized controlled trials as topic
《中医正骨》 2026 (1)
29-34,6
威海市中医药科技项目(2024Ⅲ-17)山东省中医药高层次人才培育项目(鲁卫函[2023]143号)
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