结肠癌外科手术百年嬗变与现代标准:基于循证医学规范化路径OA
A century of evolution and modern standards in colon cancer surgery:an evidence-based medicine-informed standardized approach
结肠癌的手术治疗与现代外科学的发展同步进行.从早期的结肠癌分期切除,到区域淋巴结的清扫和肠管切除长度的确定,到完整结肠系膜切除的提出及脏层筋膜的组织学发现,再到器官功能保护概念的推广,回顾历史可以发现,在外科相关技术发展的不同时期,结肠癌的标准化手术有一定的差异.近年来结肠癌手术从切除范围、手术入路,甚至标本取出等方面均发生了很大演变.在科学发展的今天,用一种术式作为结肠癌的标准化手术已不能满足精准医学的要求.随着对结肠癌认识的深入,不同时期标准化的结肠癌手术逐渐精炼为结肠癌的手术标准,如区域淋巴结清扫、10 cm原则及系膜层面切除,而这些"标准"是需要长期恪守的.
Surgical treatment of colon cancer has evolved in parallel with the progress of modern surgery.From the early practices of staged resection,through the dissection of regional lymph nodes and considerable length of colon,to the introduction of complete mesocolic excision and histologic recognition of the visceral fascia,and onward to the current emphasis on organ-function preservation,history shows that the"standard"operation for colon cancer has differed in every era of surgical innovation.In recent years,regional lymph node dissection,surgical procedures,and even methods of specimen extraction have undergone significant evolution.Relying on a unified surgical technique as the standardized procedure for colon cancer is no longer sufficient to meet the demands of precision medicine.With the development of the study of colon cancer,the standardized procedures of different eras have gradually been distilled into the fundamental surgical standards for colon cancer,such as regional lymph node dissection,the 10-cm rule,and mesocolic excision,which require long-term adherence.
叶颖江;王超
北京大学人民医院胃肠外科,北京 100044北京大学人民医院胃肠外科,北京 100044
医药卫生
结肠癌手术淋巴结清扫完整结肠系膜切除
colon cancersurgerylymphadenectomycom-plete mesocolic excision
《中国实用外科杂志》 2026 (2)
184-188,5
国家自然科学基金项目(No.82303089) National Natural Science Fund(No.82303089)
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