窄带成像技术结合电子膀胱软镜在保膀胱治疗后随访中的临床综合价值研究OA

Objective To investigate the diagnostic performance and patient compliance of narrow-band imaging(NBI)combined with electronic flexible cystoscopy in the follow-up of bladder cancer(BCa)patients after bladder-preserving therapy(BPT),and to provide evidence for optimizing follow-up strategies.Methods Clinical data of BCa patients who underwent BPT at the Harbin Medical University Cancer Hospital between January 2022 and June 2025 were retrospectively analyzed.An OLYMPUS electronic flexible cystoscope system was used to perform examinations under both white-light imaging(WLI)and NBI modes.Lesion detection rates and diagnostic performance were compared between the two imaging modalities.Patient comfort during examination was evaluated using the Visual Analog Scale(VAS),and follow-up compliance was also analyzed.Results A total of 268 BCa patients were included.A total of 808 lesions were detected,including 679 malignant lesions and 129 benign lesions.Compared with WLI,the NBI mode demonstrated significantly higher sensitivity(100.0%vs.77.5%),accuracy(86.1%vs.68.1%),and average number of detected lesions(2.95±0.85 vs.2.35±1.60).The advantages of NBI were particularly evident for micro-lesions≤0.5 cm(detection rate difference:36.6%),early-stage tumors(Ta-T1,detection rate difference:24.9%-27.5%),and low-grade lesions(detection rate difference:29.6%).Comfort evaluation showed that 79.5%of patients had VAS scores of 0-3,indicating no significant discomfort.In terms of compliance,65.7%of patients were willing to undergo the examination again.Spearman correlation analysis revealed a significant negative correlation between VAS score and compliance willingness with follow-up(r=-0.694,P<0.01).Conclusion NBI combined with electronic flexible cystoscopy demonstrates higher detection efficiency for malignant lesions during follow-up after BPT for BCa patients,while also providing good patient comfort and follow-up compliance,indicating excellent overall clinical value.