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甲状腺滤泡源性肿瘤超声诊断的难点及研究进展OA

Difficulties and research progress in ultrasonic diagnosis of follicular cell-derived thyroid neoplasms

中文摘要英文摘要

根据新版甲状腺肿瘤病理分类,滤泡源性肿瘤(FDN)涵盖良性、低风险及恶性亚型,其中恶性FDN(主要包含甲状腺滤泡癌及嗜酸细胞癌)预后显著劣于前者.然而,目前超声风险分层系统及穿刺活检对FDN均难以实现精准的良恶性鉴别.近年来,超声造影与弹性成像等其他超声成像技术的广泛应用为FDN的术前良恶性鉴别提供了可能,已涌现出大量相关研究尝试解决FDN的术前鉴别这一热点与难点问题.基于此,本文就不同模态的超声技术对FDN诊断的难点及研究进展作综述.

The updated histopathological classification of thyroid tumors recognizes follicular cell-derived thyroid neoplasms(FDN)as consisting of benign,low-risk,and malignant subtypes.Malignant FDN,mainly follicular thyroid carcinoma and oncocytic carcinoma,are linked to significantly poorer clinical outcomes when compared with benign lesions.However,conventional ultrasound risk stratification systems and fine-needle aspiration biopsy still have limitations in accurately differentiating benign from malignant FDN.In recent years,the incorporation of advanced ultrasound modalities,such as contrast-enhanced ultrasound and elastography,has offered promising ways to enhance preoperative diagnostic accuracy.A burgeoning body of research has aimed to tackle this long-standing challenge in FDN classification.This review outlines current diagnostic limitations and emphasizes recent advancements in the application of ultrasound techniques for the assessment of FDN.

贺崇;张勇跃;王淑敏

北京大学第三医院超声医学科(北京 100191)北京大学第三医院超声医学科(北京 100191)北京大学第三医院超声医学科(北京 100191)

医药卫生

甲状腺滤泡源性肿瘤超声检查超声造影弹性成像鉴别诊断

follicular cell-derived thyroid neoplasmsultrasonographycontrast-enhanced ultra-soundelastographydifferential diagnosis

《实用医学杂志》 2026 (7)

1165-1170,6

国家自然科学基金面上项目(编号:82372561)

10.3969/j.issn.1006-5725.2026.07.007

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