针灸在化疗诱发性恶心与呕吐防治中的治疗作用OA

Chemotherapy-induced nausea and vomiting(CINV)remains one of the most disruptive complications during cancer treatment,often persisting despite standard antiemetic regimens.As clinical practice seeks supplementary strategies to enhance symptom control,acupuncture and moxibustion have emerged as promising adjunctive therapies.Existing trials and meta-analyses indicate their therapeutic potential,yet the neurobiological basis for these effects has not been fully elucidated.This study synthesizes current evidence to outline how acupuncture and moxibustion intervene in the peripheral and central path-ways involved in CINV.Particular attention is given to their regulatory influence on vagal afferent sig-naling,gastrointestinal sensory pathways,and key neurotransmitter systems,such as 5-HT,SP,DA,and GABA,alongside modulation of brainstem nuclei and higher-order neural circuits implicated in emetic responses.The analysis also identifies procedural and methodological constraints in present clinical stud-ies and highlights unresolved mechanistic questions.By integrating findings from neurophysiology and oncology-related symptom research,this review offers a foundation for more precise mechanistic inves-tigations and for optimizing acupuncture-based interventions in CINV management.