基于"流湿润燥"探讨胃癌前病变OA
Precancerous Lesions of Gastric Cancer Based on"Promoting Fluid Flow to Moisten Dryness"
"流湿润燥"是刘完素根据其六气病因病机理论及玄府气液理论提出的学术思想,经张从正及后世医家完善,内涵渐趋丰富."流湿润燥"符合脾胃"燥湿相济"的生理特性与病理演变规律,本文以此为核心切入点,系统梳理其理论渊源与学术脉络,并结合"脾湿胃燥"的生理基础及胃癌前病变"气阴两虚"核心病机,进一步阐释其病机转归.燥热内结可致玄府郁闭,气液停滞,进而煎灼津液、化湿生痰;脾胃运化失司,则津液不布、气机不畅;津亏不足以濡养,则胃燥益甚;最终湿浊内停与燥热偏盛相互胶结,促进癌毒滋生.
"Promoting fluid flow to moistening dryness"is an academic thought proposed by LIU Wansu based on his theories of etiology and pathogenesis of the six qi and the Xuanfu qi-fluid,which was further refined by ZHANG Congzheng and later physicians,gradually enriching its connotations."Promoting fluid flow to moistening dryness"aligns with the physiological characteristics and pathological evolution of spleen and stomach,known as"mutual restraint and coordination of dryness and dampness".Taking this as the core entry point,this paper systematically reviews its theoretical origins and academic context.Furthermore,by integrating the physiological basis of"spleen dampness and stomach dryness"with the core pathogenesis of"qi-yin deficiency"in the precancerous lesions of gastric cancer(PLGC),the authors elaborate on the pathogenic evolution of PLGC.This paper posits that the internal binding of dry-heat can induce stagnation and blockage of Xuanfu,causing accumulation of qi and fluid,and then scorching body fluids,transforming into dampness and phlegm.Dysfunction of spleen and stomach in transporting and transforming disrupts distribution of body fluids and qi movement.Deficiency of body fluids fails to nourish the body,exacerbating stomach dryness.Ultimately,the mutual intermingling of internally retained damp-turbidity and excessive dry-heat promotes the generation of cancer toxin.
李小风;李雨;马良;张杨
黑龙江中医药大学,黑龙江哈尔滨 150036黑龙江中医药大学附属第一医院,黑龙江哈尔滨 150040黑龙江中医药大学,黑龙江哈尔滨 150036黑龙江中医药大学附属第一医院,黑龙江哈尔滨 150040
医药卫生
流湿润燥刘完素胃癌前病变炎—癌转化脾湿胃燥燥湿转化气阴两虚
promoting fluid flow to moisten drynessLIU Wansuprecancerous lesions of gastric cancerinflammation-cancer transformationspleen dampness and stomach drynessdryness-dampness transformationqi-yin deficiency
《山东中医药大学学报》 2026 (2)
162-166,5
国家自然科学基金项目(编号:81973601)黑龙江省自然科学基金项目(编号:LH2023H059)龙江科技英才春雁支持计划项目(编号:2022CYQN0027)
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