衰老异质性的研究进展OA

With the development of Chinese society,the proportion of the population aged 65 and above is increasing,and China is gradually entering an aging society.How to achieve healthy aging and how to delay aging have become important social issues.Due to the heterogeneity of aging,different individuals have different rates of aging.Aging is jointly regulated by internal and external factors.The internal factors include the twelve classic characteristics of aging,and there are multiple aging"clocks"that can indicate the level of cellular senescence.Therefore,the internal factors are clearly studied at present.The external factors include contributing factors and harmful factors.At present,the research on external factors is less and more concentrated in specific risk areas,and the research on the real situation is relatively limited.External factors interact with internal factors to influence aging.The use of multivariate cross analysis calculation to establish a comprehensive model of the interaction between internal and external factors of aging in a universal environment can provide theoretical support and technical means for the prevention and early warning of aging and related diseases.