丁型肝炎患者的临床管理OA

Hepatitis D virus(HDV),as a defective virus,relies on the envelope protein of hepatitis B virus(HBV)to complete replication and transmission.Chronic hepatitis B(CHB)patients comorbid with HDV infection may experience significant acceleration of liver disease progression and a significantly higher risk of serious complications such as liver cirrhosis and hepatocellular carcinoma(HCC)compared with the patients with CHB alone,which poses a serious threat to the life and health of patients.At present,the coverage rate of HDV screening needs to be improved,and some patients with HBV/HDV co-infection have not been found in time.Therefore,strengthening the understanding of HDV among clinicians,expanding the scope of HDV screening,identifying patients with infection in a timely manner,and performing standardized antiviral therapy and long-term follow-up management are of great significance for improving the prognosis of patients,reducing disease burden,improving the quality of life of patients,and achieving the global goal of"eliminating viral hepatitis as a public health threat by 2030".