LSaO2、BCVA、RNFL及CRA流速对视网膜静脉阻塞患者合并阻塞性睡眠呼吸暂停低通气综合征的预测价值OA

Objective To compare the differences of lowest oxygen saturation(LSaO2),best corrected visual acuity(BCVA),retinal nerve fiber layer thickness(RNFL),peak systolic velocity(PSV)and end diastolic velocity(EDV)of central retinal artery(CRA)between retinal vein occlusion(RVO)patients with and without obstructive sleep apnea hypopnea syndrome(OSAHS),and to analyze their predictive value for combined OSAHS.Methods A total of 180 patients with RVO treated from June 2020 to June 2023 were selected and divided into OSAHS group(n=83)and non-OSAHS group(n=97)according to the presence or absence of OSAHS.The baseline data,LSaO2,BCVA,RNFL,CRA-PSV,CRA-EDV and apnea hypopnea index(AHI)were compared between the two groups.The relationship of LSaO2,BCVA,RNFL,CRA-PSV,CRA-EDV with AHI in patients with RVO complicated with OSAHS was analyzed.The predictive value of LSaO2,BCVA,RNFL,CRA-PSV and CRA-EDV for the risk of RVO combined with OSAHS was evaluated.Results The body mass index,proportion of hypertension,age,proportion of hyperlipidemia and AHI in the OSAHS group were higher than those in the non-OSAHS group,while LSaO2,BCVA,RNFL,CRA-PSV and CRA-EDV were lower than those in the non-OSAHS group(P<0.05).Pearson correlation analysis showed that LSaO2,BCVA,RNFL,CRA-PSV,and CRA-EDV were negatively correlated with AHI(P<0.05).After adjusting for other factors,multivariate logistic regression analysis showed that LSaO2,BCVA,RNFL,CRA-PSV and CRA-EDV were all influencing factors of RVO combined with OSAHS(P<0.05).The area under the curve of LSaO2,BCVA,RNFL,CRA-PSV and CRA-EDV in predicting the risk of RVO combined with OSAHS was 0.917(95%CI:0.866,0.953),which was greater than that of each index alone(P<0.05).Conclusion LSaO2,BCVA,RNFL,CRA-PSV and CRA-EDV are closely related to AHI in patients with RVO complicated with OSAHS.The combination of each index is helpful to improve the predictive value for RVO complicated with OSAHS.