饲喂发酵枸杞渣对滩羊生产性能、血清生化指标、免疫指标及抗氧化性能的影响OA
Effects of Fermented Goji Berry Residue on Performance,Serum Immune Index and Antioxidant Function of Tan Sheep
为研究发酵枸杞渣对滩羊生产性能、血清生化指标、免疫指标及抗氧化性能的影响,本试验选择3~4月龄、体重为(28.26±1.03)kg的滩羊公羔48只,随机分为2组,每组24个重复.各组饲粮中分别添加0%(对照组)和4%发酵枸杞渣(试验组),进行为期68 d的饲养试验(前8 d为预饲期).结果显示,与对照组相比,试验组滩羊的平均日增重显著提高(P<0.05);血清免疫球蛋白A(IgA)含量显著升高(P<0.05),而肿瘤坏死因子-α(TNF-α)含量显著降低(P<0.05);血清丙二醛(MDA)水平显著下降(P<0.05),肝脏谷胱甘肽过氧化物酶(GSH-Px)活性显著增强(P<0.05).此外,淋巴细胞中白细胞介素-2(IL-2)、IL-6及干扰素-γ(IFN-γ)的相对表达水平均显著上调(P<0.05),而IL-4和转化生长因子-β1(TGF-β1)的表达则呈下降趋势.综上所述,饲粮中添加发酵枸杞渣可以显著提高育肥滩羊的生长性能,显著增强血清IgA、GSH-Px含量,显著降低TNF-α、MDA含量,调节免疫和抗氧化功能,从而改善动物健康,促进生长.
This experiment was conducted to study the effects of fermented goji berry residue on per-formance,serum immune indexes and antioxidant function of Tan sheep.A total of 48 ram lambs of Tan sheep,aged 3-4 months and weighing(28.26±1.03)kg,were randomly assigned to two groups,with 24 replicates per group.The dietary treatments consisted of a basal diet supplemented with 0%(control group)and 4%fermented goji berry residues(experimental group),and the trial duration was 68 days,with an 8-day pre-feeding period.The results showed that the average daily gain(ADG)of individuals in the experimental group was significantly higher than that of the control group(P<0.05).The serum im-munoglobulin A(IgA)content in the experimental group was significantly higher than that in the control group(P<0.05),while the tumor necrosis factor-alpha(TNF-α)content was significantly lower(P<0.05).Serum malondialdehyde(MDA)activity in the experimental group was significantly decreased com-pared to the control group(P<0.05),whereas the activity of glutathione peroxidase(GSH-Px)in the liver was significantly increased(P<0.05).The mRNA expression levels of IL-2,IL-6,and IFN-γ in lym-phocytes showed significant differences,with relative expression levels markedly elevated in the experi-mental group(P<0.05),whereas the relative expression levels of IL-4 and TGF-β1 tended to decrease,although not significantly.In summary,dietary supplementation with fermented goji berry residues can significantly enhance the growth performance of fattening Tan sheep,markedly improve serum immune globulin and glutathione peroxidase content,significantly reduce TNF and MDA levels,and modulate im-mune and antioxidant functions,thereby promoting animal health and growth.
李盼;詹聪;王悦;杨渝;张连全;王文亮;徐小春
北方民族大学生物科学与工程学院,食品生产与安全协同创新中心,宁夏银川 750021北方民族大学生物科学与工程学院,食品生产与安全协同创新中心,宁夏银川 750021北方民族大学生物科学与工程学院,食品生产与安全协同创新中心,宁夏银川 750021北方民族大学生物科学与工程学院,食品生产与安全协同创新中心,宁夏银川 750021宁夏朔牧盐池滩羊繁育有限公司,宁夏吴忠 751100宁夏朔牧盐池滩羊繁育有限公司,宁夏吴忠 751100北方民族大学生物科学与工程学院,食品生产与安全协同创新中心,宁夏银川 750021
农业科技
发酵枸杞渣滩羊抗氧化免疫育肥
fermented goji berry residueTan sheepantioxidationimmunizationfattening
《家畜生态学报》 2026 (3)
37-44,8
北方民族大学科学研究项目重点科研项目(2021JCYJ13)国家自然科学基金(31860625)中科院西部之光项目(XAB2021YW15)宁夏自然科学基金(2022AAC03239)
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