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从脾肾论治"肠道微生物-免疫炎症"相关流产OA

Treating Miscarriage Related to"Gut Microbiota-Immune Inflammation"from Perspective of Spleen and Kidney

中文摘要英文摘要

"脾肾互赞"理论源自李中梓《医宗必读》,强调脾肾之间相互滋生的关系.临床中常以健脾补肾法治疗多种疾病,该法也同样适用于"肠道微生物-免疫炎症"相关流产的治疗,可在养胎、安胎方面发挥重要作用.肠道微生物可能通过激活免疫炎症引发流产.健脾补肾类中药可通过调节肠道菌群、纠正Th1/Th2、Th17/Treg失衡和抑制炎症等在安胎中发挥作用.因此,临证治疗"肠道微生物-免疫炎症"相关流产时,可从脾肾虚衰入手,通过健脾补肾、清热化瘀等方法调节机体肠道微生物稳态,以达到安胎效果.

The theory of"mutual enhancement of Spleen and Kidney"originates from Li Zhongzi's Yi Zong Bi Du and it emphasizes the mutually nurturing relationship between the Spleen and Kidney.In clinical practice,the method of strengthening the Spleen and tonifying the Kidney is commonly used to treat various diseases.This method is also applicable to the treatment of miscarriages related to"gut mi-crobiota-immune inflammation",playing an important role in fetal nourishment and pregnancy stabilization.Gut microbiota may induce miscarriage by activating immune inflammation.Chinese medicines that strengthen the Spleen and tonify the Kidney can contribute to pregnancy stabilization by regulating gut microbiota,correcting Th1/Th2 and Th17/Treg imbalances,and inhibiting inflammation.There-fore,inclinical treatment of miscarriages related to"gut microbiota-immune inflammation",starting from Spleen and Kidney deficien-cy,methods such as strengthening the Spleen and tonifying the Kidney as well as clearing Heat and resolving blood stasis can be used to regulate the body's gut microbiota homeostasis to achieve fetal protection.

吉梦甜;胡小芳

河南中医药大学第一临床医学院,河南 郑州 450000河南中医药大学第一附属医院国医堂,河南 郑州 450000

医药卫生

"肠道微生物-免疫炎症"流产从脾肾论治安胎

"gut microbiota-immune inflammation"miscarriagetreatment from perspective of Spleen and Kidneypregnancy stabili-zation

《中医学报》 2026 (4)

786-790,5

10.16368/j.issn.1674-8999.2026.04.117

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