首页|期刊导航|巴楚医学|循证管理路径对中老年血脂异常患者的干预效果评价

循证管理路径对中老年血脂异常患者的干预效果评价OA

Evaluation of the Intervention Effect of an Evidence-Based Management Pathway in Middle-Aged and Elderly Patients with Dyslipidemia

中文摘要英文摘要

目的:探讨基于临床指南的慢病管理模式对中老年血脂异常患者的干预效果.方法:选取2022年4月—2023年4月在宜昌市中心人民医院人才健康管理中心体检的中老年血脂异常患者183例,随机分为对照组(n=87)和干预组(n=96).其中对照组仅进行降脂治疗,干预组则在对照组的基础上实施基于《中国血脂管理指南(基层版2024年)》的慢病管理.进行为期1年随访,比较两组患者血脂异常指标的改善情况.结果:随访1年后,干预组不良生活方式(缺乏运动、超重或肥胖)比例较干预前减少(37.50%vs 54.17%、47.92%vs 71.88%),服药依从性(96.88%vs 89.58%)、血压达标率(64.58%vs 48.96%)、低密度脂蛋白胆固醇(LDL-C)达标率(92.71%vs 0%)均较干预前提高(均P<0.05).干预组和对照组对比发现,干预组不良生活方式(缺乏运动、超重或肥胖)(37.50%vs 57.47%、47.92%vs 68.97%)、服药依从性(96.88%vs 82.76%)、总胆固醇(TC)达标率(97.92%vs 72.41%)、甘油三酯(TG)达标率(83.33%vs 68.97%)、LDL-C 达标率(92.71%vs 41.38%)均优于对照组(均P<0.05).结论:通过对血脂异常患者实施慢病管理,可以对危险因素如缺乏运动、超重或肥胖等进行有效干预,同时提高服药依从性,对TC、TG及LDL-C达标率等指标进行有效控制,为血脂异常慢病管理模式的构建提供实践经验和理论依据.

Objective:To explore the intervention effect of a chronic disease management model based on clinical guidelines on middle-aged and elderly patients with dyslipidemia.Methods:A total of 183 middle-aged and elderly patients with dyslipidemia who underwent physical examination at the Talent Health Management Center of Yichang Central People's Hospital from April 2022 to April 2023 were selected and randomly divided into a control group(n=87)and an intervention group(n=96).The control group received only lipid-lowering treatment,while the intervention group received chronic disease management based on the"Chinese Guidelines for Lipid Management(Primary Care Edition,2024)"in addition to the same treatment as the control group.A one-year follow-up was conducted.The improvement in dyslipidemia indicators was compared between the two groups.Results:After one year of follow-up,the intervention group showed significant reductions in the proportions of unhealthy lifestyle behaviors,including physical inactivity(37.50%vs 54.17%)and overweight or obesity(47.92%vs 71.88%).Medication adherence(96.88%vs 89.58%),blood pressure control rate(64.58%vs 48.96%),and low-density lipoprotein cholesterol(LDL-C)target attainment rate(92.71%vs 0%)were significantly improved compared with baseline(all P<0.05).Compared with the control group,the intervention group demonstrated better outcomes in terms of unhealthy lifestyle behaviors(physical inactivity:37.50%vs 57.47%,overweight or obesity:47.92%vs 68.97%),medication adherence(96.88%vs 82.76%),and target attainment rates for total cholesterol(TC)(97.92%vs 72.41%),triglycerides(TG)(83.33%vs 68.97%),and LDL-C(92.71%vs 41.38%)(all P<0.05).Conclusion:Implementing chronic disease management in patients with dyslipidemia can effectively intervene in risk factors such as lack of exercise,and overweight or obesity,while improving medication adherence and enhancing control over indicators such as TC,TG,and LDL-C compliance rates.This study provides practical experience and theoretical basis for the construction of the chronic disease management model for dyslipidemia.

金晶;李书国;罗俊;李馨欣;覃倩;严晓琴;李融融;张静;黄鹤飞

三峡大学第一临床医学院[宜昌市中心人民医院]干部保健科&宜昌市人才健康管理中心,湖北宜昌 443003三峡大学第一临床医学院[宜昌市中心人民医院]干部保健科&宜昌市人才健康管理中心,湖北宜昌 443003三峡大学第一临床医学院[宜昌市中心人民医院]干部保健科&宜昌市人才健康管理中心,湖北宜昌 443003三峡大学第一临床医学院[宜昌市中心人民医院]干部保健科&宜昌市人才健康管理中心,湖北宜昌 443003三峡大学第一临床医学院[宜昌市中心人民医院]干部保健科&宜昌市人才健康管理中心,湖北宜昌 443003三峡大学第一临床医学院[宜昌市中心人民医院]干部保健科&宜昌市人才健康管理中心,湖北宜昌 443003三峡大学第一临床医学院[宜昌市中心人民医院]干部保健科&宜昌市人才健康管理中心,湖北宜昌 443003三峡大学第一临床医学院[宜昌市中心人民医院]干部保健科&宜昌市人才健康管理中心,湖北宜昌 443003三峡大学第一临床医学院[宜昌市中心人民医院]干部保健科&宜昌市人才健康管理中心,湖北宜昌 443003

医药卫生

慢病管理危险因素血脂异常中老年

chronic disease managementrisk factorsdyslipidemiamiddle-aged and elderly

《巴楚医学》 2026 (1)

70-75,6

四大慢病重大专项(2024ZD0524600)中央引导地方科技发展专项(2022BGE237)湖北省区域科技创新计划项目(2025EIA015)湖北省自然科学基金创新发展联合基金项目(2025AFD280)

10.3969/j.issn.2096-6113.2026.01.009

评论