基于络病理论探析脑胶质瘤的中医辨治思路OA
Analysis of the Traditional Chinese Medicine Diagnosis and Treatment Approach for Gliomas Based on the Theory of Collateral Diseases
脑胶质瘤为神经系统常见恶性肿瘤,是全球病死率最高的恶性肿瘤之一,至今仍面临治愈率低、复发率高、预后极差的临床困境.本文从络病理论出发,对脑胶质瘤的病因病机进行深入研究,总结出其以髓减络虚为本,以痰浊阻络、血瘀滞络、外风袭络、内风扰络、癌毒损络为标,并根据"络以通为用"理论,提出基本治法为络虚通补、益精填髓,辛泄畅络、豁痰化瘀,通络消积、祛风解毒.
Glioma,as a common malignant tumor of the nervous system and one of the malignant tumors with the highest mortality rates globally,still faces the persistent clinical dilemma of low cure rate,high recurrence rate,and extremely poor prognosis to this day.Based on the theory of collateral diseases and the guiding ideology of"smoothly regulating the brain collaterals",this paper conducts in-depth research on the etiology and pathogenesis of glioma,and summarizes that the essence of its etiology and pathogenesis lies in marrow deficiency and collateral asthenia,while its manifestation is the damage to the brain collaterals by toxins.According to the theory that"the collaterals should be kept unobstructed for their normal function",the basic treatment principles are proposed as follows:tonifying the deficiency of the collaterals and replenishing essence and marrow;dispersing with acrid herbs to smooth the collaterals,resolving phlegm and removing blood stasis;freeing the collaterals to dissipate masses,expelling wind and detoxifying.
齐帆;孟凯强;吕晶;黄岚;赵晓平;范小璇;冯照群
广州中医药大学,广东 广州 510006||陕西中医药大学,陕西 咸阳 712046陕西中医药大学,陕西 咸阳 712046陕西中医药大学,陕西 咸阳 712046陕西中医药大学,陕西 咸阳 712046陕西中医药大学附属医院,陕西 咸阳 712000陕西中医药大学,陕西 咸阳 712046陕西中医药大学附属医院,陕西 咸阳 712000
医药卫生
脑胶质瘤络病理论畅调脑络髓减络虚毒损脑络
GliomaTheory of collateral diseasesRegulating and unblocking brain collateralsDeficiency of the marrow and the collateralsDamage to the brain collaterals by toxins
《中医药学报》 2026 (3)
1-5,5
国家自然科学基金项目(81873288)陕西省中西医结合临床协作创新项目(2020-ZXY-007)陕西省省级院士工作站建设项目-吴以岭院士工作站(陕组通字[2019]49 号)陕西省中医脑病临床医学研究中心建设项目(陕科社发[2017]176 号)国家中医药管理局高水平中医药重点学科建设项目(国中医药人教函[2023]85 号)
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