首页|期刊导航|中西医结合慢性病杂志|毫火针针刺"突三针"治疗原发性甲状腺功能减退理论基础与作用机制

毫火针针刺"突三针"治疗原发性甲状腺功能减退理论基础与作用机制OA

Theoretical Basis and Mechanism of Millifire Needling"Tu Sanzhen"in Treating Primary Hypothyroidism

中文摘要英文摘要

甲状腺功能减退症(简称甲减)在中国患病率较高,约为17.8%,女性及老年人群更为常见.目前,西医治疗以甲状腺激素替代疗法为主,但存在药物依赖、剂量调整复杂以及特殊人群用药受限等问题.毫火针针刺"突三针"作为一种非药物疗法,融合中医辨病与辨证理论,为甲减的治疗提供了新思路."突三针"由天突、水突、扶突三穴组成,源于靳三针疗法,通过局部刺激甲状腺区域,起到疏通气血、化痰散结的作用,从而改善甲减症状.毫火针结合了传统火针的温通效应与现代毫针的精细操作,兼具温阳益气、调和气血阴阳的功效,尤其适用于脾肾阳虚型甲减患者.其作用机制可能涉及调节下丘脑-垂体-甲状腺轴功能、改善免疫紊乱及促进局部气血运行.临床研究表明毫火针联合西药可显著提升甲状腺激素水平,降低促甲状腺激素,且疗效优于单一疗法.一例59岁女性患者经12周治疗后,促甲状腺激素从11.49 μIU/mL降至4.15 μIU/mL,优甲乐剂量逐步减少直至停药,症状明显改善.尽管针灸疗法在缓解甲减症状方面展现出独特优势,但现有研究样本量较小,且缺乏长期随访数据.未来需开展大样本随机对照试验,进一步验证其疗效及持久性,以优化临床治疗方案.毫火针针刺"突三针"为甲减治疗提供了安全有效的替代选择,具有重要的临床价值.

Hypothyroidism has a relatively high prevalence in China,approximately 17.8%,and is more common among women and the elderly.Currently,Western medicine primarily employs thyroid hormone replacement therapy,which presents issues such as drug dependence,complex dosage adjustments,and limited application in special populations.As a non-pharmacological therapy,millifire needling of"Tu Sanzhen"(Three Prominence Needles),integrating traditional Chinese medicine disease differentiation and syndrome differentiation theory,offers a novel approach for hypothyroidism treatment."Tu Sanzhen"consists of the Tiantu(CV22),Shuitu(ST10),and Futu(LI18)acupoints,originating from the Jin's Three Needles technique.It acts by locally stimulating the thyroid region to regulate qi and blood,resolve phlegm and dissipate nodules,thereby alleviating hypothyroid symptoms.Millifire needling combines the warming and unblocking effects of traditional fire needling with the precise manipulation of modern filiform needles,offering the dual benefits of warming yang and boosting qi,as well as harmonizing qi,blood,yin,and yang.It is particularly suitable for patients with the spleen-kidney yang deficiency type of hypothyroidism.Its mechanism of action may involve regulating the function of the hypothalamic-pituitary-thyroid(HPT)axis,improving immune dysregulation,and promoting local qi and blood circulation.Clinical studies indicate that combining millifire needling with Western medication can significantly increase thyroid hormone levels and reduce thyroid-stimulating hormone(TSH),with superior efficacy compared to monotherapy.In a case of a 59-year-old female patient,after 12 weeks of treatment,TSH decreased from 11.49 μIU/mL to 4.15 μIU/mL,the levothyroxine dosage was gradually reduced until discontinuation,and symptoms markedly improved.Although acupuncture therapy demonstrates unique advantages in relieving hypothyroid symptoms,current research has small sample sizes and lacks long-term follow-up data.Future large-scale randomized controlled trials are necessary to further validate its efficacy and durability,in order to optimize clinical treatment protocols.Millifire needling of"Tu Sanzhen"provides a safe and effective alternative for hypothyroidism treatment,holding significant clinical value.

于会源;王健;赖倚文;刘峻

辽宁中医药大学,辽宁 沈阳 110847辽宁中医药大学附属医院,辽宁 沈阳 110032辽宁中医药大学附属医院,辽宁 沈阳 110032辽宁中医药大学附属医院,辽宁 沈阳 110032

医药卫生

原发性甲状腺功能减退症毫火针突三针针刺作用机制

primary hypothyroidismmillifire needletu sanzhenacupuncturemechanism of action

《中西医结合慢性病杂志》 2026 (2)

41-46,6

国家中医药管理局全国名老中医药专家传承工作室项目(国中医药人教函[2022]304号)辽宁省科技厅项目(2024JH2/102500042)辽宁省教育厅项目(JYTMS20231825)辽宁省科技厅联合基金面上资助计划项目(2023-MSLH-189)

10.26950/j.issn.2097-5031.2026.02.007

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