首页|期刊导航|中国中药杂志|抗氧化剂在肉桂挥发油包合物喷雾干燥中的保护作用研究

抗氧化剂在肉桂挥发油包合物喷雾干燥中的保护作用研究OA

Protective effect of antioxidants in spray drying of cinnamon essential oil inclusion complexes

中文摘要英文摘要

喷雾干燥技术广泛应用于挥发油包合物的制备过程中,该技术在干燥过程中由于高温环境,往往会导致包合物中挥发油的氧化损失.针对这一问题,该研究以肉桂挥发油制备的包合物为研究对象,通过测定硫代巴比妥酸反应物质值(TBARS)和过氧化值(POV),从没食子酸辛酯、L-抗坏血酸棕榈酸酯、没食子酸丙酯等 6 种抗氧化剂中初步筛选出能够显著增强包合物中挥发性成分保留率的抗氧化剂,作为挥发油包合物喷雾干燥过程的"保护剂".进一步地,结合15 d的高温稳定性实验与GC-MS分析,深入研究不同浓度抗氧化剂对包合物中挥发性成分保留率、高温稳定性及其成分的影响.结果表明,没食子酸辛酯和没食子酸丙酯2 种抗氧化剂展现出其在有效保护包合物挥发性成分方面的潜力.此外,特定浓度的抗氧化剂能显著减少包合物中挥发性成分的损失,提升保护效果.没食子酸辛酯和没食子酸丙酯分别可提升包合物中挥发性成分保留率至 90.38%和 87.96%(对照组为 78.36%).在高温稳定性测试中,0.04%的抗氧化剂对挥发油的保护效果尤为明显.通过GC-MS分析确认,抗氧化剂的加入不会干扰挥发油的化学成分.因此,挥发油包合物的制备过程中添加适量抗氧化剂,可以有效保护挥发油免受氧化损失,提高包合物中挥发性成分保留率和稳定性.

Spray drying is widely employed in the preparation of essential oil inclusion complexes.However,due to the high-temperature environment during drying,this technology often results in oxidative loss of essential oils within these inclusion complexes.To address this issue,this study utilized the inclusion complexes prepared from cinnamon essential oil and measured thiobarbituric acid reactive substances(TBARS)value and peroxide value(POV).Among the six antioxidants such as octyl gallate,L-ascorbyl palmitate,and propyl gallate,the antioxidants that could significantly enhance the retention rate of volatile components in the spray drying process of essential oil inclusion complexes were screened out and used as"protective agents"during the spray drying process.Furthermore,by combining a 15-day high-temperature stability test with GC-MS analysis,the effects of varying antioxidant concentrations on the retention rate of volatile components,high temperature stability,and their components in the inclusion complexes were investigated.The results revealed that both octyl gallate and propyl gallate demonstrated considerable potential in effectively preserving the volatile components.In addition,these antioxidants at specific concentrations markedly reduced the loss of volatile components and enhanced the protecting effect.The retention rates of volatile components reached 90.38%and 87.96%for octyl gallate and propyl gallate,respectively,compared to 78.36%in the control group.The protective effect was particularly pronounced at an antioxidant concentration of 0.04%under the high-temperature stability test.GC-MS analysis confirmed that the incorporation of antioxidants did not interfere with the chemical composition of the essential oil.Therefore,the addition of appropriate concentrations of antioxidants during the preparation of essential oil inclusion complexes can effectively mitigate oxidative loss and improve both the retention and stability of volatile components.

胡恢权;万娜;刘玉华;顾晶晶;刘英;陈海燕;廖嘉宝;伍振峰

江西中医药大学 现代中药制剂教育部重点实验室,江西 南昌 330004||经典名方现代中药创制全国重点实验室,江西 南昌 330004江西中医药大学 现代中药制剂教育部重点实验室,江西 南昌 330004||经典名方现代中药创制全国重点实验室,江西 南昌 330004华润三九现代中药制药有限公司,广东 惠州 516000||中药配方颗粒安徽省重点实验室,安徽 淮北 235000赣江新区智药善和科技有限公司,江西 南昌 330029江西中医药大学 现代中药制剂教育部重点实验室,江西 南昌 330004||经典名方现代中药创制全国重点实验室,江西 南昌 330004江西中医药大学 现代中药制剂教育部重点实验室,江西 南昌 330004||经典名方现代中药创制全国重点实验室,江西 南昌 330004华润三九现代中药制药有限公司,广东 惠州 516000||中药配方颗粒安徽省重点实验室,安徽 淮北 235000江西中医药大学 现代中药制剂教育部重点实验室,江西 南昌 330004||经典名方现代中药创制全国重点实验室,江西 南昌 330004

抗氧化剂没食子酸辛酯没食子酸丙酯挥发油稳定性包合物喷雾干燥

antioxidantoctyl gallatepropyl gallateessential oil stabilityinclusion complexspray drying

《中国中药杂志》 2026 (6)

1565-1572,8

国家自然科学基金面上项目(82474091)江西省重点研发计划项目(20243BBI91013)江西中医药大学研究生创新专项(XJ-202503)

10.19540/j.cnki.cjcmm.20251028.301

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