基于"药辅合一"理念的固体颗粒协同稳定中药挥发油Pickering乳液调控机制研究进展OA

The"combination of medicines and excipients"is a unique medication concept proposed in the field of pharmaceutics and therapeutics,showcasing the holistic thinking and clinical application wisdom of traditional Chinese medicine(TCM)compound medication.It is not only an important feature that distinguishes it from chemical drug preparations,but also one of the core advantages of TCM preparations.Pickering emulsions,as effective and ideal carriers,can utilize natural macromolecules with"combination of medicines and excipients"characteristics as solid particle emulsifiers to replace conventional surfactants,demonstrating remarkable efficacy in enhancing the stability of essential oils in TCM.Based on the framework of the"combination of medicines and excipients"concept,this study systematically explored the specific mechanisms underlying the solid particle types and stabilization systems of Pickering emulsions for essential oils from TCM,analyzed the factors influencing the stability of emulsions,and explored their potential application value,aiming to provide theoretical basis for promoting formulation development and clinical application of essential oils from TCM.